Comparative analysis of three plasmids from strain MS-17-188 and their role in antimicrobial resistance.

Background: strain MS-17-188 was isolated from a deceased catfish from East Mississippi and showed resistance to florfenicol, tetracyclines and a sulphonamide. WGS of strain MS-17-188 revealed three plasmids (pPSMS-171881, pPSMS-171882 and pPSMS-171883).

Objectives: To accurately determine the impact of three plasmids found in strain MS-17-188 on the dissemination of antibiotic resistance genes and to provide insights into the molecular structure of these plasmids.

Characterisation and mobilisation of IncA/C plasmid-mediated antibiotic resistance in Edwardsiella ictaluri.

Objectives: Edwardsiella ictaluri is an important pathogen in farmed raised catfish. Recently, we showed that resistance to tetracycline and florfenicol in the E. ictaluri MS-17-156 strain isolated from channel catfish was facilitated by acquisition of a 135 kb plasmid (named pEIMS-171561).