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Publications by authors named "Munir Iqba"

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Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma metastases.
Joakim W Karlsson Vasu R Sah Roger Olofsson Bagge Irina Kuznetsova Munir Iqba

Elife

September 2024

Article Synopsis
  • * This study aimed to improve immunotherapy for UM by identifying specific tumor-reactive T cells in liver metastases using advanced methods like single-cell RNA sequencing and patient-derived xenograft models.
  • * The results showed that tumor-reactive T cells were found in both activated and exhausted groups, and insights gained can help enhance cell therapy approaches and identify useful markers for treatment.
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