Penetration of Pazufloxacin into the Fluid of Suction Blisters Induced in Human Skin.

We investigated the pharmacokinetics of pazufloxacin (PZFX) in the fluid of suction blisters induced in the skin of 6 healthy male volunteers after a 200mg oral dose of PZFX. The time to reach the maximum concentration (t) of PZFX in plasma was 0.7 hours, and the maximum concentration (C) was 2.