Publications by authors named "Muneretto C"

: New-onset postoperative atrial fibrillation (POAF) is the most common complication after cardiac surgery, occurring approximately in one-third of the patients. This study considered all-comer patients who underwent cardiac surgery to build a predictive model for POAF. : A total of 3467 (Center 1) consecutive patients were used as a derivation cohort to build the model.

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Heart failure (HF) remains a significant public health issue, with heart transplantation (HT) being the gold standard treatment for end-stage HF. The increasing use of mechanical circulatory support, particularly left ventricular assist devices (LVADs), as a bridge to transplant (BTT), presents new perspectives for increasingly complex clinical scenarios. This study aimed to compare long-term clinical outcomes in patients in heart failure with reduced ejection fraction (HFrEF) receiving an LVAD as BTT to those undergoing direct-to-transplant (DTT) without mechanical support, focusing on survival and post-transplant complications.

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Article Synopsis
  • The study examines the effectiveness of different energy sources used in the Cox-maze IV surgical procedure for treating atrial fibrillation (AF), specifically comparing bipolar radio-frequency (BRF), cryoenergy (Cryo), and a combination of both.
  • Results indicate that patients who underwent cryoablation had significantly lower rates of AF recurrence after both 6 months (6.73% for Cryo) and 4 years (6.14% for Cryo) compared to those treated with BRF and the combined method.
  • The findings suggest that cryoablation may lead to better long-term sinus rhythm restoration in patients undergoing AF ablation compared to bipolar radiofrequency ablation alone.
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  • Cardiac hemangioma is a rare, benign tumor that can be asymptomatic or cause symptoms depending on its location and interaction with nearby structures.
  • A case study describes a 79-year-old patient diagnosed with right cardiac hemangioma after experiencing severe symptoms like fluid buildup and heart failure.
  • The tumor was successfully removed using cardiopulmonary bypass, leading to a favorable outcome after 12 months, highlighting its unusual size and location near the tricuspid valve.
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  • - Myocardial revascularization, either through percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery, effectively alleviates symptoms and enhances quality of life when paired with guideline-directed medical therapy.
  • - Hybrid coronary revascularization is a combination approach that employs CABG for the left anterior descending artery (LAD) and PCI for other coronary vessels, targeting patients who are not ideal candidates for traditional CABG.
  • - The procedure is best performed in a collaborative setting with a specialized heart team, focusing on complete revascularization, particularly in patients with complex multivessel coronary disease, leveraging advanced drug-eluting stents.
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  • This study compared the outcomes of two aortic valve replacement methods—sutureless aortic valve replacement (SUAVR) and transcatheter aortic valve implantation (TAVI)—in patients with small aortic annulus (SAA).
  • A total of 622 patients were analyzed, and after matching for key characteristics, 146 patients from each group were evaluated for all-cause death at 36 months and other complications.
  • Results indicated that the TAVI group had a higher rate of all-cause death (21% vs. 12.2%) and more major adverse cardiovascular and cerebrovascular events (32.6% vs. 18.1%), while both methods showed similar hemodynamic performances.
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EuroSCORE II (ES2) is a reliable tool for preoperative cardiac surgery mortality risk prediction; however, a patient's age, a surgical procedure's weight and the new devices available may cause its accuracy to drift. We sought to investigate ES2 performance related to the surgical risk and late mortality estimation in patients who underwent aortic valve replacement (AVR) with sutureless valves. : Between 2012 and 2021, a total of 1126 patients with isolated aortic stenosis who underwent surgical AVR by means of sutureless valves were retrospectively collected from six European centers.

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Fontan circulation presents significant challenges for patients with congenital heart disease, often necessitating heart transplantation (HTX) due to deteriorating functionality across multiple organ systems. However, the impact of prior Fontan palliation on HTX outcomes remains poorly understood, with early mortality rates suggesting a heightened risk. The aim of our study is to evaluate the long-term results after heart transplantation in patients with univentricular congenital heart disease previously palliated with Fontan circulation.

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To develop risk scoring models predicting long-term survival and major adverse cardiovascular and cerebrovascular events (MACCEs), including myocardial infarction and stroke after coronary artery bypass grafting (CABG). All 4,821 consecutive patients who underwent isolated CABG at Lankenau between January 2005 and July 2021 were included. MACCE was defined as all-cause mortality + myocardial infarction + stroke.

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Atrial fibrillation (AF) has been reported as a major cause of cardiac morbidity and mortality, and significantly reduces the quality of life in symptomatic patients. Current guidelines recommend antiarrhythmic drugs and catheter ablation (CA) as first-line therapy. Despite CA showed to be associated with lower incidence of peri-procedural complications, rhythm outcomes are far from optimal.

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Document Reviewers: Rudolf A. de Boer (CPG Review Co-ordinator) (Netherlands), P. Christian Schulze (CPG Review Co-ordinator) (Germany), Elena Arbelo (Spain), Jozef Bartunek (Belgium), Johann Bauersachs (Germany), Michael A.

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Introduction: The use of Del Nido Cardioplegia (DNC) has been extended in the latest years from pediatrics to adult cardiac surgery with encouraging results. We sought to investigate clinical and biochemical outcomes in adult patients who underwent cardiac surgery with different degrees of complexity who received DNC for myocardial protection.

Methods: Data on one-thousand patients were retrospectively collected from 2020 to 2022.

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Background: The management of an enlarged left atrium (LA) in mitral valve (MV) disease with atrial fibrillation (AF) is still being debated. It has been postulated that a reduction in LA size may improve patient outcomes. This meta-analysis aimed to assess rhythm and clinical outcomes of combined surgical AF treatment with or without LA volume reduction (LAVR) in patients undergoing MV surgery.

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Article Synopsis
  • - Recent studies indicate that while transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) have similar short-term outcomes in intermediate and low-risk patients, TAVI shows poorer long-term results after five years.
  • - This study analyzed mid- to long-term outcomes of 2,123 patients with isolated aortic stenosis receiving either sutureless valve replacement or TAVI, with a focus on comparing mortality rates and adverse events.
  • - Findings revealed that patients who underwent sutureless valve replacement had lower rates of 30-day mortality (2.13% vs 4.64%) and overall cardiac-related mortality (10.2% vs 19.2%) compared to
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Aims: Timing and surgical strategies in acute infective endocarditis are still questionable. We sought to investigate clinical outcomes of patients undergoing mitral valve repair (MVR) compared with mitral valve replacement [mitral valve prosthesis (MVP)] for acute infective endocarditis.

Methods: From 2004 to 2019, 109 consecutive patients with acute mitral valve infective endocarditis were retrospectively investigated.

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Background: Recent trials showed that TAVI is neither inferior nor superior to surgical aortic valve replacement. The aim of this study was to evaluate the outcomes of Sutureless and Rapid Deployment Valves (SuRD-AVR) when compared to TAVI in low surgical risk patients with isolated aortic stenosis.

Methods: Data from five European Centers were retrospectively collected.

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Background: Antiarrhythmic drugs and transcatheter ablation in atrial fibrillation (AF) provide suboptimal rhythm control with a not negligible rate of failure in paroxysmal AF (PAF) and nonparoxysmal AF (n-PAF) at midterm and long-term follow-up. This study evaluated the safety profile and long-term efficacy of thoracoscopic ablation in patients with lone AF.

Methods: A consecutive 153 patients with lone AF were prospectively enrolled and underwent thoracoscopic surgical ablation.

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Objectives: New technologies for the treatment of Aortic Stenosis are evolving to minimize risk and treat an increasingly comorbid population. The Sutureless Perceval Valve is one such alternative. Whilst short-term data is promising, limited mid-term outcomes exist, until now.

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Background: Mid- and long-term rhythm outcomes of catheter ablation (CA) for atrial fibrillation (AF) are reported to be suboptimal. Minimally invasive surgical off-pump ablation (MISOA), including both thoracoscopic and trans-diaphragmatic approaches, has been developed to reduce surgical invasiveness and overcome on-pump surgery drawbacks. We sought to compare the efficacy and safety of MISOA and CA for AF treatment.

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Patients in hemodialysis with an arm arteriovenous fistula undergoing coronary artery bypass grafting (CABG) with an internal thoracic artery have been reported to suffer from coronary-subclavian steal (CSS) during dialysis session. However, its occurrence is still debated. A systematic literature review was performed to identify all studies investigating the occurrence of a CSS event in this subset of patients.

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Background: The predictive role of chest radiographs in patients with suspected coronary artery disease (CAD) is underestimated and may benefit from artificial intelligence (AI) applications.

Objectives: To train, test, and validate a deep learning (DL) solution for detecting significant CAD based on chest radiographs.

Methods: Data of patients referred for angina and undergoing chest radiography and coronary angiography were analysed retrospectively.

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