Publications by authors named "Munds R"

The origin of primates has long been associated with an increased emphasis on manual grasping and touch. Precision touch, facilitated by specialized mechanoreceptors in glabrous skin, provides critical sensory feedback for grasping-related tasks and perception of ecologically-relevant stimuli. Despite its importance, studies of mechanoreceptors in primate hands are limited, in part due to challenges of sample availability and histological methods.

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  • Empirical data on how body mass impacts immune defense against infections is sparse; larger organisms were previously thought to have weaker immune responses, but new studies suggest they may actually have stronger defenses.
  • The safety factor hypothesis proposes that larger organisms evolved stronger immune systems due to their higher risk of exposure to pathogens.
  • In this study, researchers found that larger primates showed a greater increase in the expression of immune genes in response to infection compared to smaller primates, supporting the safety factor hypothesis and highlighting the complex relationship between body size and immunity.
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  • The original publication discusses the main themes and findings of a specific research study.
  • It highlights the methodology used and the significance of the results in the context of the relevant field.
  • Key conclusions and implications for future research or practice are also presented, providing a comprehensive overview of the subject matter.
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  • Herpesviruses are large DNA viruses used as gene therapy tools and are increasingly being developed as vaccine vectors due to their ability to stimulate immune responses.
  • Recent applications include vaccines targeting infectious agents like Ebola and HIV, as well as potential cancer treatments, bolstered by advances in recombinant DNA technology and immunology.
  • Continued research into herpesvirus biology and innovative virology techniques is essential to improve the safety and effectiveness of these vaccine vectors while addressing their current limitations.
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Genetic analysis of historical museum collections presents an opportunity to clarify the evolutionary history of understudied primate groups, improve taxonomic inferences, and inform conservation efforts. Among the most understudied primate groups, slow and pygmy lorises (genera and ) are nocturnal strepsirrhines found in South and Southeast Asia. Previous molecular studies have supported five species, but studies using morphological data suggest the existence of at least nine species.

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  • COVID-19, caused by SARS-CoV-2, has a complicated relationship with dogs, as their lower susceptibility is linked to the differences in ACE2 receptors compared to humans.
  • Studies show that dogs are less likely to spread COVID-19 due to low binding affinity between their ACE2 and the virus's spike protein.
  • While dogs can potentially transmit the virus, the review emphasizes the importance of prevention and examines the possibility of using detection dogs to identify infected individuals through various samples.
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  • The study investigates the variations in cone ratios of color vision among catarrhine primates, focusing on rhesus macaques, which possess uniform trichromacy allowing them to see red, green, and blue wavelengths.
  • Researchers analyzed the genetic factors influencing the L:M and S cone ratios using RNA data, finding a generally consistent L:M ratio of about 1.03:1, with negligible genetic effects on this ratio.
  • Although female macaques exhibited slightly larger L:M ratios, S cone ratios showed significant genetic variance and heritability, providing insights into the genetic underpinnings of color vision variability in primates.
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Organisms use color for camouflage, sexual signaling, or as a warning sign of danger. Primates are one of the most vibrantly colored Orders of mammals. However, the genetics underlying their coat color are poorly known, limiting our ability to study molecular aspects of its evolution.

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Extensive phylogenetic studies have found robust phylogenies are modeled by using a multi-gene approach and sampling from the majority of the taxa of interest. Yet, molecular studies focused on the lorises, a cryptic primate family, have often relied on one gene, or just mitochondrial DNA, and many were unable to include all four genera in the analyses, resulting in inconclusive phylogenies. Past phylogenetic loris studies resulted in lorises being monophyletic, paraphyletic, or an unresolvable trichotomy with the closely related galagos.

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Objectives: Based on vocalization recordings of an unknown galago species, our main objectives were to compare morphology and call structure with known closely-related taxa and describe a new species of galago.

Materials And Methods: We conducted field surveys in three forest habitats along the escarpment region in western Angola (Kumbira Forest, Bimbe Area, and Northern Scarp Forest), and examined galago specimens from museums worldwide. We digitized and analyzed calls using Avisoft SASLab Pro software.

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More species of nocturnal primates are now recognized than in the past, because many are cryptic species. Subtle morphological disparities, such as pelage pattern and color variation, vocal cues, and genetics have aided in elucidating the number of diagnosable species in a genus. The slow lorises (genus Nycticebus) once included only two species, but recent taxonomic studies resulted in the description of three additional species; further incompletely explored variability characterizes each of the currently described species.

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Using DNA-tagged mutagenesis to improve heterologous protein production in Aspergillus oryzae. Fungal Genetics and Biology 29, 28-37. Restriction enzyme-mediated integration (REMI) has been employed as a mutagen to generate two insertion libraries in an Aspergillus oryzae strain expressing a Thermomyces lanuginosus lipase.

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