The alpha defensin lateral flow test is effective in predicting eradication of periprosthetic joint infection after surgical debridement.

The primary aim of this study was to assess the utility of the alpha defensin lateral flow (ADLF) test for predicting the eradication of PJI after surgical debridement. The secondary aim was to describe the reliability of ADLF test in diagnosis of PJI intra- operatively. A prospective observational study was conducted in three independent orthopaedic centres.

Diagnostic value of routine pre-operative investigations used in combination in the diagnosis of periprosthetic joint infection.

The primary aim of this study was to assess the diagnostic accuracy of joint aspiration culture, serum C-reactive protein (CRP) and serum erythrocyte sedimentation rate (ESR), individually, and in combination for the diagnosis of periprosthetic joint infection (PJI). A consecutive patient series with pre-operative inflammatory marker levels, an aspiration culture of either hip or knee arthroplasty and intra-operative culture samples from subsequent revision surgery was compiled. This retrospective patient cohort analysis included 128 aspiration.

The Importance Of Multi-site Intra-operative Tissue Sampling In The Diagnosis Of Hip And Knee Periprosthetic Joint Infection - Results From A Single Centre Study.

: The primary aim of this study was to determine whether the tissue type and anatomical location of intra-operative samples influences the accuracy of culture in the diagnosis of periprosthetic joint infection (PJI). The secondary aim was to create a predictive model of PJI using other known patient variables. : A retrospective cohort of 3460 intra-operative samples from 887 patients was identified.

Patterns of changes in femoral bone mineral density up to five years after hip resurfacing.

This is a prospective study of 26 patients (29 hips) on the patterns of change in the Bone Mineral Density (BMD) in various zones of the femoral neck and proximal femur five years after hip resurfacing. We have found that BMD continues to positively change up to five years after hip resurfacing. This was observed primarily in the trochanteric and superior neck regions.

Socio-economic impact of Birmingham hip resurfacing on patient employment after ten years.

Birmingham hip resurfacing is an attractive option for treatment of arthritis in young and active patients. The aim of this study was to assess the socio-economic impact of Birmingham hip resurfacing on their employment and work intensity at ten years. A cohort of 90 consecutive patients with 100 Birmingham hip resurfacing, performed by single surgeon, were reviewed prospectively.

Judet's quadricepsplasty, surgical technique, and results in limb reconstruction.

Quadricepsplasty has been described by Thompson and Judet to improve flexion in severely ankylosed knees. Judet's technique has potential advantages because it is less damaging to the quadriceps mechanism and addresses the problem of external fixator pin site tethering on the lateral side of the thigh. The outcome of Judet's quadricepsplasty was assessed in 10 consecutive patients who were treated with external fixation either as a primary treatment (three patients) or as a secondary treatment for nonunion or malunion (seven patients) in a limb reconstruction unit.

Outcome of complex fractures of the tibial plateau treated with a beam-loading ring fixation system.

Fine-wire external fixation is accepted as a minimally invasive technique, which can provide better outcomes than traditional open methods in the management of complex fractures of the tibial plateau. Available fixators vary in their biomechanical stability, and we believe that a stable beam-loading system is essential for consistently good outcomes. We assessed, prospectively, the clinical, radiological and general health status of 20 of 21 consecutive patients with complex fractures of the tibial plateau who had been treated using a standard protocol, with percutaneous screw fixation and a neutralisation concept with a fine wire beam-loading fixator allowing early weight-bearing.

Treatment of displaced bicondylar tibial plateau fractures (OTA-41C2&3) in patients older than 60 years of age.

Objective: To investigate the outcome (clinical, radiographic, and general health status) of the surgical treatment of displaced bicondylar tibial plateau fractures (OTA-41C) in patients >60 years old.

Design: Prospective cohort study.

Setting: Limb reconstruction service, university teaching hospital.