Finite element analysis of pulse sharpening effect of gyromagnetic nonlinear transmission line based on Landau-Lifshitz-Gilbert equation.

Ferrite-loaded gyromagnetic nonlinear transmission line (GNLTL) provides a possible option to compress an input pulse to a narrower width for its remarkable sharpening effect. However, it is difficult to accurately predict the output of the GNLTL due to the complex interaction between the magnetic moment of ferrite and the bias magnetic field. In this paper, a finite element model of the GNLTL is established based on the Landau-Lifshitz-Gilbert equation to investigate the performance of the GNLTL.

[Clinical efficacy of different waves of electroacupuncture on knee osteoarthritis and its effect on TGF-β1 in joint fluid].

Objective: To observe the therapeutic effects of different waves of electroacupuncture (EA) on knee osteoarthritis (KOA), and to explore the mechanism of different waves of EA on promoting cartilage repair.

Methods: Ninety- seven patients with KOA were randomly divided into a dilatational wave group (32 cases, 2 cases dropped off), a continuous wave group (32 cases, 2 cases dropped off) and a discontinuous wave group (33 cases, 3 cases dropped off). The same acupoints of Xuehai (SP 10), Liangqiu (ST 34), Dubi (ST 35) and Neixiyan (EX-LE 4) were selected in the three groups.

Development of a compact high-voltage pulser for hypervelocity microparticles injector.

This paper highlights the development of a high-voltage pulser that utilizes a zero-voltage-switching (ZVS) circuit and diode split flyback transformer to produce high-voltage DC pulses for a hypervelocity microparticle injector. In our circuit, the resonant inverter of the ZVS circuit is coupled to the diode split flyback transformer to generate a voltage of 10-40 kV. A power MOSFET (IXTQ 110N10P) is placed in the circuit to switch the variable DC input power supply to get a repetitive pulse output.

Warm sparse-dense wave inhibits cartilage degradation in papain-induced osteoarthritis through the mitogen-activated protein kinase signaling pathway.

Cartilage degradation is an important in the pathogenesis of osteoarthritis (OA). Abnormal activation of the mitogen-activated protein kinase (MAPK) signaling pathway in chondrocytes promotes an inflammatory response, resulting in the release of chondral matrix-degrading enzymes that accelerate the degradation of cartilage. As a non-pharmaceutical and non-invasive physical therapy regimen, warm sparse-dense wave (WSDW) has been successfully used for the treatment of OA.

Field-reversed configuration formed by in-vessel θ-pinch in a tandem mirror device.

We describe a field reversed configuration (FRC) experiment featuring in-vessel θ-pinch coils and open-field-line plasmas confined in a tandem mirror. Two FRCs, formed near the west and the east mirror throats of a central cell, are ejected toward the mid-plane for colliding and merging. Each FRC consists of four groups of pulsed power supplies and four groups of coils, having diameters 35, 35, 40, and 45 cm.

A high voltage pulse generator based on silicon-controlled rectifier for field-reversed configuration experiment.

A high voltage pulse generator based on a silicon-controlled rectifier has been designed and implemented for a field reversed configuration experiment. A critical damping circuit is used in the generator to produce the desired pulse waveform. Depending on the load, the rise time of the output trigger signal can be less than 1 μs, and the peak amplitudes of trigger voltage and current are up to 8 kV and 85 A in a single output.

Ion cyclotron resonance heating (ICRH) systems for the Keda Mirror with AXisymmetry (KMAX).

In this paper, we describe the engineering work involved in constructing two ion cyclotron resonance heating (ICRH) systems for use in the Keda Mirror with AXisymmetry tandem mirror experiment. Because they offer an effective and robust heating method, ICRH systems have been widely used in a variety of plasma experiments. The goal of our system is to heat the hydrogen plasma contained in the central cell using the fundamental ion cyclotron frequency.

Needle-knife therapy improves the clinical symptoms of knee osteoarthritis by inhibiting the expression of inflammatory cytokines.

Knee osteoarthritis (KOA) is a degenerative joint disease that occurs mainly in the elderly population. However, there are currently no effective treatments for treating this condition. In this study, the efficacy of needle-knife therapy, a technique of traditional Chinese medicine that has been widely used to treat KOA was investigated.

Icariin promotes bone formation via the BMP-2/Smad4 signal transduction pathway in the hFOB 1.19 human osteoblastic cell line.

Icariin, the main active compound of the traditional Chinese medicine, Epimedium, is commonly used for the clinical treatment of osteoporosis. However, the precise molecular mechanism of the therapeutic effect of icariin has not been elucidated. The aim of this study was to examine the effect of icariin on cell viability, alkaline phosphatase (ALP) activity, the amount of calcified nodules, and to delineate the molecular mechanism of icariin-enhanced bone formation by investigating the expression of bone morphogenic protein-2 (BMP-2), Smad4, Cbfa1/Runx2, osteoprotegerin (OPG), receptor activator of nuclear factor κ-B ligand (RANKL) and the OPG/RANKL ratio in the hFOB 1.

Clinical study on the treatment of knee osteoarthritis of Shen-Sui insufficiency syndrome type by electroacupuncture.

Objective: To study the clinical effificacy of electroacupuncture (EA) on treating knee osteoarthritis (KOA) of Shen ()-Sui () insuffificiency (SSI) syndrome type.

Methods: A total of 245 patients (279 knees) of KOA-SSI were randomly assigned to two groups by lottery: 141 knees in the treatment group and 138 knees in the control group. The treatment group was managed with EA at the dominant points of Neixiyan (Ex-LE4) and Waixiyan (Ex-LE5) as well as the conjugate points of Xuanzhong (GB39) and Taixi (KI3) for 30 min, once a day, with 15 days as one course; 2 courses were applied with a 5-day interval in between.

[Effects of time factors on acupoint sticking therapy for preventing and treating bronchial asthma].

Objective: To observe the influence of time factors on acupoint sticking therapy for preventing and treating bronchial asthma.

Methods: Seventy-one cases were randomly divided into a dog days group (n= 30), a Sanjiu days group (n=21) and a daily days group (n=20). They were all treated with ginger moxibustion plus acupoint sticking of Chinese medicine at Dazhui (GV 14) and Feishu (BL 13) etc.

[Effect of OA kneepad on apoptosis genes Bcl-2 and p53 expression in articular cartilage cells of experimental knee osteoarthritis].

Objective: To study the effects of kneepad on expression of Bcl-2 and p53 mRNA of chondrocyte in white rabbits with knee osteoarthritis, so as to explore and treatment mechanism of OA kneepad on apoptosis of chondrocytes of rabbits with knee osteoarthritis in molecular degree.

Methods: Forty-four Japanese healthy 6-month-old rabbits (equal male and female,the weight ranging from 2 to 2.2 kg) were used to establish knee osteoarthritis models by modified Hulth method.

[Effects of shouwu-huanjing recipe on human sperm motility and fertility in vitro].

Objective: To observe the effect of Shouwu-Huanjing Recipe(SWHJR) medicated serum on human sperm motility and fertility in vitro.

Methods: Human sperm was co-cultured with SWHJR medicated serum in vitro. Human sperm motility was evaluated by computer-assisted semen analysis(CASA).