Comparative analysis of antioxidant status in diabetic patients with and without insulin resistance.

Diabetes mellitus (DM) is a metabolic disorder characterized by insulin resistance, where hyperglycemia is believed to trigger oxidative stress, contributing to insulin function impairment. This study aimed to assess and compare levels of malondialdehyde (MDA), glutathione (GSH), and uric acid in diabetic patients with and without insulin resistance and to assess the correlation with fasting blood sugar (FBS) and lipid profiles. Significant variations were found in MDA, uric acid, and GSH levels between insulin-resistant and non-resistant diabetic groups (p<0.

The impact of omentin-1 gene polymorphisms (rs2274907 and rs2274908) on serum lipid concentrations and coronary artery disease in a sample of Iraqi individuals (A pilot study).

Background: Coronary artery disease (CAD) is the primary cause of death worldwide. It is mainly caused by atherosclerosis that initiates from a genetic-environmental interaction. Studies highlighted the association of numerous gene polymorphisms with CAD.