Publications by authors named "Mun-Yee Chong"

Article Synopsis
  • A study explored how the consumption of papaya affects immune responses differently in healthy males and females, highlighting the role of sex hormones.
  • In females, papaya intake led to a decrease in natural killer (NK) cells and an increase in B cells, linked to elevated estrogen levels, while males showed increased NK cell activity and T helper cells.
  • The findings suggest that sex hormones, such as progesterone and testosterone, may significantly influence immune responses after papaya consumption, indicating distinct immune profiles between genders.
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Differences in gender immune response have resulted in differences in immune protection and susceptibility to inflammatory diseases. Cultured peripheral blood mononuclear cells (PBMC) are widely used in immunomodulation studies, yet the influence of gender is usually not considered. We examined the effect of in vitro culture and phytohaemagglutinin (PHA) stimulation on PBMC lymphocyte subsets using flowcytometry.

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Fruit and vegetables have therapeutic potential as they dampen inflammation, have no known side-effects and as whole foods have prospective additive and synergistic benefits. Th1 (IFN-γ(+) CD4(+))/Th2 (IL-4(+)CD4(+)) T cells play a vital role in mediating inflammatory responses and may be regulated by regulatory T cells (Tregs). Effects of Carica papaya on cells of healthy individuals were determined using flow cytometry methods.

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