Prevalence of Methicillin-Resistant and Associated Risk Factors among Patients with Wound Infection at Referral Hospital, Northeast Ethiopia.

Background: The spectrums of infections due to methicillin-resistant are manifold and are associated with worse outcomes. A study on the prevalence of these pathogens and their sensitivity patterns will give updated information which is very helpful for health personnel responsible in the management of patients and timely monitoring of the emergence of resistant bacteria. Hence, the study aimed at assessing the prevalence of methicillin-resistant and associated factors among patients with wound infection at Dessie Referral Hospital.

Galanin Receptors as Drug Target for Novel Antidepressants: Review.

Galanin (GAL) is a 29-amino-acid neuropeptide that serves multiple physiological functions throughout the central and peripheral nervous system. Its role involves in a range of physiological and pathological functions including control of food intake, neuro-protection, neuronal regeneration, energy expenditure, reproduction, water balance, mood, nociception and various neuroendocrine functions. The use of currently available antidepressant drugs raises concerns regarding efficacy and onset of action; therefore, the need for antidepressants with novel mechanisms is increasing.

Antidiabetic Effect of Germinated Seed Extract in Streptozotocin-Induced Diabetic Mice.

Background: seed has been used in traditional practices to treat various ailments, including diabetes mellitus, in Ethiopia. Previous phytochemical screening studies indicated that germination of the seed of contains more bioactive constituents compared to raw seeds. The aim of this study was to investigate the antidiabetic activity of an aqueous methanol extract of germinated seed extract in streptozotocin (Stz)-induced diabetic mice.