Correction: Bellu et al. Smart Nanofibers with Natural Extracts Prevent Senescence Patterning in a Dynamic Cell Culture Model of Human Skin. 2020, , 2530.

In the original publication [...

Rock Slope Stability Analysis Using Terrestrial Photogrammetry and Virtual Reality on Ignimbritic Deposits.

Puerto de Cajas serves as a vital high-altitude passage in Ecuador, connecting the coastal region to the city of Cuenca. The stability of this rocky massif is carefully managed through the assessment of blocks and discontinuities, ensuring safe travel. This study presents a novel approach, employing rapid and cost-effective methods to evaluate an unexplored area within the protected expanse of Cajas.

Limitations and consequences of public health models centred on hospitals and lacking connections with territorial and home-based social and health services.

Background: Delayed discharge from hospital to home or other care institutions is a significant problem and has been investigated in the international scientific literature for many years. Behind this condition is a health care system based on a hospital-centered concept characterized by a lack of territorial health and social welfare services. This phenomenon causes two different problems: an excessive length of hospital stay, resulting in slow turnover of bed utilization; and overcrowding in emergency rooms (ERs).

Sensitivity and Specificity of Qualitative Visual Field Tests for Screening Visual Hemifield Deficits in Right-Brain-Damaged Stroke Patients.

A timely detection of visual hemifield deficits (VHFDs; hemianopias or quadrantanopias) is critical for both the diagnosis and treatment of stroke patients. The present study determined the sensitivity and specificity of four qualitative visual field tests, including face description, confrontation tests (finger wiggle), and kinetic boundary perimetry, to screen large and dense VHFDs in right-brain-damaged (RBD) stroke patients. Previously, the accuracy of qualitative visual field tests was examined in unselected samples of patients with heterogeneous aetiology, in which stroke patients represented a very small fraction.

Modeling Phenological Phases across Olive Cultivars in the Mediterranean.

Modeling phenological phases in a Mediterranean environment often implies tangible challenges to reconstructing regional trends over heterogenous areas using limited and scattered observations. The present investigation aimed to project phenological phases (i.e.

Sensitivity and Specificity of the Brentano Illusion Test in the Detection of Visual Hemi-Field Deficits in Patients with Unilateral Spatial Neglect.

Stroke survivors with right-brain damage (RBD) often present with attentional deficits such as left unilateral spatial neglect. Some patients also present with contralesional visual hemi-field deficits. A late detection of visual hemi-field deficits (VHFD) contributes to hampering neurorehabilitation and functional outcome of patients with neglect.

Superior growth traits of invaded (Caribbean) versus native (Red sea) populations of the seagrass .

Unlabelled: The seagrass is native to the Red Sea. It invaded the Mediterranean over the past century and most of the Caribbean over the last two decades. Understanding the main drivers behind the successful invasiveness of has become crucial.

Multidimensional Results and Reflections on CAR-T: The Italian Evidence.

The present study aims at defining the economic and organizational impacts of the introduction of chimeric antigen receptor T-cell therapy (CAR-T) in Italy, for the management of diffuse large B-cell lymphoma (DLBCL) patients in third-line therapy, defining the overall level of sustainability for both hospitals and the National Healthcare System (NHS). The analysis focused on CAR-T and Best Salvage Care (in the following BSC), assuming the Italian hospital and NHS perspectives, over a 36-month time horizon. Process mapping and activity-based costing methodologies were applied to collect the hospital costs related to the BSC and CAR-T pathways, including adverse event management.

Modelling solution for estimating aeration energy of wastewater treatment plants.

Energy costs in the wastewater industry are increasing due to increasing trends in electricity rates and more stringent requirements for effluent quality. Wastewater aeration process is typically the largest energy consumer of the treatment plant and the optimization of the aeration process can offer significant savings for the wastewater treatment plants (WWTPs). Utilization of dynamic models can offer optimization solutions for improving the energy efficiency and process performance.

The influence of light and temperature on detritus degradation rates for kelp species with contrasting thermal affinities.

Kelp detritus fuels coastal food webs and may play an important role as a source of organic matter for natural carbon sequestration. Here, we conducted ex situ and in situ manipulations to evaluate the role of temperature and light availability in the breakdown of detrital material. We examined degradation rates of two North Atlantic species with contrasting thermal affinities: the 'warm water' kelp Laminaria ochroleuca and the 'cool water' Laminaria hyperborea.

Natural Compounds and PCL Nanofibers: A Novel Tool to Counteract Stem Cell Senescence.

Tissue homeostasis mainly depends on the activity of stem cells to replace damaged elements and restore tissue functions. Within this context, mesenchymal stem cells and fibroblasts are essential for maintaining tissue homeostasis in skin, in particular in the dermis. Modifications in collagen fibers are able to affect stem cell features.

Expression of Structural Flavonoid Biosynthesis Genes in Dark-Blue and White Myrtle Berries ( L.).

Within the myrtle ( L.) species, different genotypes may produce dark-blue berries or white berries depending on the peel color upon ripening. One dark-blue cultivar and one white myrtle cultivar were used to study the molecular mechanisms underlying flavonoid biosynthesis.

Numerous new records of tropical non-indigenous species in the Eastern Mediterranean highlight the challenges of their recognition and identification.

New data on 52 non-indigenous mollusks in the Eastern Mediterranean Sea is reported. sp. (aff.

Control of postharvest diseases caused by Penicillium spp. with myrtle leaf phenolic extracts: in vitro and in vivo study on mandarin fruit during storage.

Background: In the postharvest handling of horticultural commodities, plant extracts with fungicidal activity are a valid alternative to synthetic fungicides. The fungicidal activity of myrtle leaf extracts from eight cultivars was studied in vitro against Penicillium digitatum, Penicillium italicum, and Penicillium expansum and on artificially inoculated mandarins with green and blue molds during storage for 12 days at 20 °C and 90% RH.

Results: Hydroxybenzoic acids, hydrolysable tannins, and flavonols were identified by high-performance liquid chromatography (HPLC).

Smart Nanofibers with Natural Extracts Prevent Senescence Patterning in a Dynamic Cell Culture Model of Human Skin.

Natural cosmetic products have recently re-emerged as a novel tool able to counteract skin aging and skin related damages. In addition, recently achieved progress in nanomedicine opens a novel approach yielding from combination of modern nanotechnology with traditional treatment for innovative pharmacotherapeutics. In the present study, we investigated the antiaging effect of a pretreatment with natural extract combined with a polycaprolactone nanofibrous scaffold (NanoPCL-M) on skin cell populations exposed to UV.

Mineral composition of plant as influenced by genotype and thermal regime.

grows in humid and saline warm regions of Mediterranean area showing high adaptability but less information is available on resistance to chilling temperatures.Potted plants of five clones (MAR1, GIO1, SAN3, PAL1, and FAN3) were cultivated during 30 months in four localities (Oristano, Tempio, Sassari, and Villasor). Every 6 months, leaves, stems and roots of plants were the object of mineral composition analysis (N, P, Na, K, Ca, Mg, Cu, Zn, Fe, and Mn).

Chemotaxonomic Evaluation by Volatolomics Analysis of Fifty-Two Genotypes of L.

A population of 52 genotypes of Myrtle ( L.), selected in the framework of a domestication program and growing in the same collection field at Oristano (Central Western Sardinia, 39°54' N 8°35' E), was analyzed by GC/MS for leaf essential oil composition. The chemical composition of essential oils was quite variable with a number of compounds ranging from 31 to 78 depending on cultivar.

Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions.

Nutraceuticals present in food are molecules able to exert biological activity for the prevention and treatment of various diseases, in form of pharmaceutical preparations, such as capsules, cream, or pills. L. is a spontaneous Mediterranean evergreen shrub, widely known for the liqueur obtained from its berries rich in phytochemicals such as tannins and flavonoids.

Modeling grid fields instead of modeling grid cells : An effective model at the macroscopic level and its relationship with the underlying microscopic neural system.

A neuron's firing correlates are defined as the features of the external world to which its activity is correlated. In many parts of the brain, neurons have quite simple such firing correlates. A striking example are grid cells in the rodent medial entorhinal cortex: their activity correlates with the animal's position in space, defining 'grid fields' arranged with a remarkable periodicity.

Polyphenols, from Antioxidants to Anti-Inflammatory Molecules: Exploring a Network Involving Cytochromes P450 and Vitamin D.

Inflammatory response represents one of the main mechanisms of healing and tissue function restoration. On the other hand, chronic inflammation leads to excessive secretion of pro-inflammatory cytokines involved in the onset of several diseases. Oxidative stress condition may contribute in worsening inflammatory state fall, increasing reactive oxygen species (ROS) production and cytokines release.

Chemical Composition of Myrtle ( L.) Berries Essential Oils as Observed in a Collection of Genotypes.

Myrtle ( L.) is a shrub spontaneously growing in the Mediterranean area. The leaf and fruit content of essential oils and phenolic compounds justify the wide use of the plant as medicinal and aromatic.