Publications by authors named "Mukesh Subhash Patil"
Pharm Nanotechnol
March 2023
Article Synopsis
- The study focused on creating a liquid self-microemulsifying drug delivery system (SMEDDS) for eprosartan mesylate, a poorly soluble drug, using specific surfactants and oil phases to enhance solubility and absorption.*
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- Various methods including phase diagram analysis and central-composite design were employed to optimize the formulation, and multiple parameters like particle size and drug release rates were measured to evaluate effectiveness.*
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- Results indicated that the SMEDDS formulation significantly improved the drug's release and bioavailability compared to traditional solid formulations, achieving a relative bioavailability increase of about 152% in rat studies.*
