Power Efficient Random Access for Massive NB-IoT Connectivity.

Sensors enabled Internet of things (IoT) has become an integral part of the modern, digital and connected ecosystem. Narrowband IoT (NB-IoT) technology is one of its economical versions preferable when low power and resource limited sensors based applications are considered. One of the major characteristics of NB-IoT technology is its offer of reliable coverage enhancement (CE) which is achieved by repeating the transmission of signals.

Hydralazine modifies Aβ fibril formation and prevents modification by lipids in vitro.

Lipid oxidative damage and amyloid β (Aβ) misfolding contribute to Alzheimer's disease (AD) pathology. Thus, the prevention of oxidative damage and Aβ misfolding are attractive targets for drug discovery. At present, no AD drugs approved by the Food and Drug Administration (FDA) prevent or halt disease progression.

Lipid oxidation and modification of amyloid-β (Aβ) in vitro and in vivo.

Oxidative damage and amyloid-β (Aβ) protein misfolding are prominent features of Alzheimer's disease (AD). In vitro studies indicated a direct linkage between these two features, where lipid oxidation products augmented Aβ misfolding. We tested this linkage further, mimicking specific conditions present in amyloid plaques.