Publications by authors named "Muhammet Kosker"

Article Synopsis
  • The study investigates multisystem inflammatory syndrome in children (MISC) related to COVID-19, focusing on comparing clinical and laboratory characteristics of children hospitalized in ICU versus those who were not.
  • Conducted from June 2021 to January 2022, the observational study included 601 patients, with 157 requiring ICU care, revealing significant differences in demographics, lab results, and disease features.
  • Key findings showed that older age groups and higher levels of certain inflammatory markers increased the likelihood of ICU admission, highlighting the severe impact of MISC on children's health.
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Background: The pathogenesis and clinical manifestations of the multisystem inflammatory syndrome in children (MIS-C) has not yet been fully elucidated and there is no clear consensus on its treatment yet.

Objectives: To evaluate our patients diagnosed with MIS-C and present them to the literature in order to contribute to the better understanding of this new disease, which entered paediatric practice with the SARS-CoV-2 peak.

Methods: In this study, 17 MIS-C cases diagnosed according to the Centers for Disease Control and Prevention criteria were included.

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Aim: Urinary tract infections are the most common genitourinary tract disease in children, and inappropriate antibiotic and/or dose selection increase the likelihood of resistance. The aim of this study was to determine the prevalence of urinary tract infection pathogens, patterns of resistance to antibiotics, and empirical treatment options.

Material And Methods: Between January 2013 and December 2017, urine culture and antibiogram results of pediatric patients aged 0 days to 16 years were analyzed retrospectively.

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Article Synopsis
  • Colistin is a crucial antibiotic for treating multi-drug resistant gram-negative bacteria, but its side effects, particularly nephrotoxicity, in premature neonates are not well-studied.
  • A retrospective review of 47 premature neonates revealed that 17% developed acute kidney injury (AKI), with gestational age and the use of aminoglycosides being linked to its occurrence.
  • Post-treatment, there was a significant decrease in magnesium levels and an increase in the frequency of hypomagnesemia and elevated AST, indicating electrolyte imbalances are more common in this patient group after colistin use.
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Aim: Acute respiratory tract infections are among the most common infectious diseases worldwide. Respiratory viruses are the leading cause of respiratory infections in children. Herein, we aimed to determine the epidemiologic and clinical feautures of viral agents among hospitalized children with lower respiratory tract infections.

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Background/aim: The aim of this study is to evaluate the effect of biologic drugs on the tuberculin skin test in patients with juvenile idiopathic arthritis.

Materials And Methods: A total of 234 biologic drug-using juvenile idiopathic arthritis patients and 45 healthy controls were enrolled in the study. The tuberculin skin test results of the patients, which had been routinely provided during follow-up, were obtained from the patient files.

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Objectives: Acute otitis media (AOM) is predominantly a disease of childhood and one of the common reasons for prescribing antibiotics. Ear pain is the main symptom of AOM, with the result that parents frequently seek immediate medical assistance for their children. Antibiotic therapy for AOM does not provide symptomatic relief in the first 24 hours, and analgesics are commonly recommended for relieving the pain associated with AOM.

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The objective of this study was to determine the rate, independent risk factors, and outcomes of healthcare-associated infections in pediatric patients. This study was performed between 2011 and 2014 in pediatric clinic and intensive care unit. 86 patients and 86 control subjects were included in the study.

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Background: As a multisystem infectious disease, there is an inflammation, which causes increase in acute phase reactants in brucellosis. The mean platelet volume (MPV), platelet distribution width (PDW), red cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been identified as markers of inflammation. The present study aimed to evaluate diagnostic values of these biomarkers in brucella arthritis (BA).

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Primary diffuse leptomeningeal gliomatosis is a disease with an aggressive course that can result in death. To date, 82 cases have been reported. Here, the case of a 3-year-old male patient presenting with strabismus, headache, and restlessness is reported.

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Tularemia is a zoonotic disease of the northern hemisphere. Oculoglandular tularemia is the rarest form, comprising 1.4-4.

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Article Synopsis
  • The study aimed to assess the impact of high doses of betamethasone administered either intra-amniotically or through fetal injections on the lung function of neonates in a goat model before preterm delivery.
  • Despite the treatment, the group receiving intra-amniotic betamethasone showed a high incidence of stillbirths and lung damage compared to control, while maternal administration improved lung pressure-volume metrics.
  • The arterial blood gas analysis indicated that the control group suffered from acid-base imbalances, highlighting the varied effects of the different dosing routes on neonatal outcomes.
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Objective: To compare the prevalence of the metabolic syndrome (MS) in Turkish obese children and adolescents by using three different definitions and to assess the risk factors through a retrospective evaluation of anthropometric and laboratory parameters.

Methods: Sixty hundred and fourteen obese patients (307 male, 307 female; mean age: 11.3±2.

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