Interventions for the prevention of mycobacterium avium complex in adults and children with HIV.

Background: Mycobacterium avium complex (MAC) infection is a common complication of advanced acquired immunodeficiency syndrome (AIDS) disease and is an independent predictor of mortality and shortened survival.

Objectives: To determine the effectiveness and safety of interventions aimed at preventing MAC infection in adults and children with HIV infection.

Search Methods: We searched MEDLINE, EMBASE, and The Cochrane Library (search date December 2012).

Interventions for HIV-associated nephropathy.

Background: Human immunodeficiency virus-associated nephropathy (HIVAN) is the most common cause of end stage kidney disease (ESKD) in human immunodeficiency virus-1 (HIV-1) serotype patients and it mostly affects patients of African descent. It rapidly progresses to ESKD if untreated. The goal of treatment is directed toward reducing HIV-1 replication and/or slowing the progression of chronic kidney disease.

Interventions for HIV-associated nephropathy.

Background: Human immunodeficiency virus associated nephropathy (HIVAN) is the most common cause of end stage kidney disease (ESKD) in Human immunodeficiency virus-1 (HIV-1) serotype patients and it mostly affects patients of African descent. It rapidly progresses to ESKD if untreated. The goal of treatment is directed toward reducing HIV-1 replication and/or slowing the progression of chronic kidney disease.