Publications by authors named "Muhammed Hamdi Uyar"
In our study, we aimed to evaluate the effect of high-dose intravenous anakinra treatment on the development of thrombotic events in severe and critical COVID-19 patients. This retrospective observational study was conducted at a tertiary referral center in Aksaray, Turkey. The study population consisted of two groups as follows; the patients receiving high-dose intravenous anakinra (anakinra group) added to background therapy and the patients treated with standard of care (SoC) as a historical control group.
View Article and Find Full Text PDFIntroduction: In this study, we aimed to evaluate the safety and efficacy of combination treatment of high-dose intravenous anakinra and baricitinib in patients with critically ill COVID-19.
Material And Methods: This retrospective observational study was conducted in a tertiary center with diagnosis of COVID-19 patients.Study population consisted of patients with positive polymerase chain reaction and computer tomography findings compatible with COVID-19 as well as critical illness.
Article Synopsis
- The study investigates the effectiveness of high-dose intravenous anakinra in treating severe COVID-19 compared to standard care, focusing on its impact on outcomes like ICU admissions and mortality.
- Conducted in a tertiary center, the research involved matching patients receiving anakinra with those on standard care, ensuring comparability in demographics and baseline characteristics.
- Results showed a significant reduction in ICU admissions and mortality rates for the anakinra group, indicating it as a safe and effective treatment for severe COVID-19 cases.