Publications by authors named "Muhammed Bahaeddin Dortbudak"
This investigate goals are to establish the utility of brain-specific biomarkers (GFAP and S100B) in vivo and to assess the brain damage in C. cerebralis-infected goats using histopathological and immunopathological methods. The animal material of the study consisted of 10 healthy and 20 Coenurus cerebralis infected female hair goats.
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- Allergic rhinitis (AR) is a common chronic disease that is increasing in prevalence, and this study examined how naringenin could protect against AR in rats.
- Thirty-two rats were used in the experiment, with one control group and three other groups subjected to AR induction, treated with either a reference medication or naringenin.
- Results indicated that naringenin significantly reduced symptoms, lowered serum IgE and cytokines associated with inflammation, and improved nasal tissue structure compared to the untreated AR group, suggesting naringenin may be a viable treatment option for AR.
Purpose: Ovarian ischemia-reperfusion (IR) damage continues to be a serious infertility problem. The oxidative stress plays central role in the development of IR injuries. Activation of antioxidants decreases IR injuries; however, the efficacy of antioxidant agents remains controversial.
View Article and Find Full Text PDFThe present study aims to examine the possible beneficial effects of gallic acid (GA) against doxorubicin-induced cardiotoxicity in the experimental model. Rats were weighed and divided into groups. Groups as following; control, gallic acid (GA), doxorubicin (DOX) and GA + DOX groups.
View Article and Find Full Text PDFIschemia reperfusion (I/R) injury which causes kidney dysfunction is one of the most studied diseases directly linked to oxidative stress. In this regard, it is important to protect cells against damage by inducing antioxidant response. Herein, we aimed to evaluate the therapeutic roles and possible mechanisms of propolis and boric acid in kidney I/R injury based on relevant basic research and clinical studies.
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- This study aimed to explore the effects of hesperidin and thymol, which have antioxidant and anti-inflammatory properties, on rats with allergic rhinitis induced by ovalbumin.
- Thirty adult rats were divided into groups for a 7-day treatment with different agents, including saline and desloratadine, along with hesperidin and thymol, and nasal symptoms were assessed on day 22.
- Results showed that hesperidin and thymol significantly reduced nasal symptoms and improved inflammatory markers compared to the positive control group, indicating their potential therapeutic effects on allergic rhinitis.