Publications by authors named "Muhammed Aziz"
A synergistic investigation of azo-thiazole derivatives incorporating thiazole moieties: a comprehensive exploration of their synthesis, characterization, computational insights, solvatochromism, and multimodal biological activity assessment.
Dara Muhammed Aziz Sangar Ali Hassan Alla Ahmad M Amin Media Noori Abdullah Karzan Qurbani Shujahadeen B Aziz
RSC Adv
November 2023
Article Synopsis
- A series of new azo-thiazole derivatives (3a-c) were synthesized and characterized using various spectroscopic methods.
- The compounds showed promising biological activities, particularly 3a and 3c with strong antibacterial effects, outperforming azithromycin, and 3b demonstrating significant wound healing capabilities.
- Molecular docking and dynamics simulations revealed that these compounds closely bind to the 1KZN protein, suggesting their potential as effective new therapeutic agents based on their bioactivity and structural properties.
Objective: The purpose of this study was to determine the long-term neurodevelopmental outcome in fetuses with severe tachy- or bradyarrhythmia.
Study Design: This was a follow-up study to assess the neurologic, mental, and psychomotor development in cases with fetal cardiac arrhythmia.
Results: A total of 44 fetuses were diagnosed with fetal tachy- or bradyarrhythmia: 28 fetuses had supraventricular tachycardia (SVT); 7 fetuses had atrial flutter (AF), and 9 fetuses had atrioventricular block (AVB).