Fatal Intoxications Due to Administration of Isosorbide Tablets Contaminated with Pyrimethamine.

In January 2012, 664 cases of pyrimethamine toxicity and 151 deaths were reported among cardiac patients that had recently received free medicines from pharmacy of Punjab Institute of Cardiology, Lahore, Pakistan. These patients, ages ranged from 58 to 75 years, were prescribed simvastatin, clopidogrel, aspirin soluble, isosorbide mononitrate, and amlodipine. On examination of medications being given to them, it was found that a particular batch of isosorbide mononitrate tablets was contaminated with 50 mg pyrimethamine.

Hair analysis of an unusual case of Chloroquine intoxication.

A dead body of middle aged man was exhumed from 6.5 month earth-grave. Autopsy findings were non-specific as the body was completely putrefied.

Methyl 5-bromo-2-hy-droxy-benzoate.

The title compound, C(8)H(7)BrO(3), is almost planar (r.m.s.