Publications by authors named "Muhammad Zaka Ul Haq"
Article Synopsis
- COVID-19 poses a higher mortality risk for individuals with diabetes, severe obesity, and cardiovascular disease, potentially due to chronic inflammation linked to type 2 diabetes.
- This study involved 350 patients with type 2 diabetes hospitalized for moderate-severe COVID-19, comparing the effects of pioglitazone against a placebo over 28 days, focusing on severe clinical outcomes and inflammation levels.
- Although pioglitazone reduced certain inflammatory markers, it did not significantly improve outcomes, as more patients treated with it required ICU care and showed no notable difference in CRP reduction compared to those on placebo.
Rhabdomyolysis is an uncommon but potentially life-threatening medical condition. The acute muscle breakdown leads to the release of toxic muscle contents which can damage the kidneys and can cause the development of acute kidney injury (AKI) and fatal electrolyte imbalances associated with high morbidity and mortality. There are a variety of causes including exposure to extremely hot weather, toxins, trauma, certain drugs, and rarely endocrine disorders in particular thyroid dysfunction.
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