Effect of gestational diabetes and maternal hypertension on gross morphology of placenta.

Background: Gestational diabetes is much more common than pre-existing diabetes i.e. it complicates 2% to 5% of pregnancies.

Ocular defects in first generation of ethanol exposed albino rats and its penetrance into third generation.

Background: The objective of this study was to observe the ocular teratogenic effects of alcohol on the third generation in albino rats.

Methods: This study was carried out at department of Anatomy, Basic Medical Sciences Institute, JPMC Karachi from 1996--98. 36 pregnant female rats were divided into a treated and a control group (18 in each).

Effects of ciprofloxacin on secondary ossification centers in juvenile Wistar albino rats.

Background: Administration of quinolone therapy is controversial during juvenile age as stated by earlier workers. The fluroquinolones are currently not indicated for young children, because of the arthropathy and adverse effect on growing cartilage shown by studies. However the effects of ciprofloxacin on secondary ossification centers has remained undocumented.

Effects of maternal smoking on placental morphology.

Background: Maternal smoking is one of leading causes of premature labour and low birth weight babies. Nicotine and carbon monoxide both induce degenerative changes as well as premature aging of placenta. Degenerative changes induce increased amount of collagen in chorionic villi and increased thickness of subtrophoblastic basement membrane.

Effects of carbimazole on morphology of rat adrenals.

Objective: Study was conducted to investigate the effects of (i) carbimazole and (ii) simultaneous administration of thyroxine (thyroid hormone analogue) on the morphology of rat adrenals.

Design: A prospective case-control study.

Place And Duration Of Study: Department of Anatomy,Basic Medical Sciences Institute (BMSI), JPMC, Karachi, during a period of six weeks.

Microscopic analysis of epidermal melanocytes in human abdominal skin.

Objective: Microscopic analysis of epidermal melanocytes in human abdominal skin with respect to age and sex.

Design: Cross sectional study.

Place And Duration Of Study: Department of Anatomy.