Microwave-Induced Synthesis of Bioactive Nitrogen Heterocycles.

There are many different applications of heterocyclic molecules in the pharmaceutical and materials science fields, which make them an important family of compounds. Among these heterocyclic compounds, nitrogen-containing heterocyclic (N-heterocyclic) compounds have attracted a lot of interest among researchers due to their various applications across a wide variety of fields. Many studies have been performed over the past few years to study the synthesis of N-heterocycles under different reaction conditions, such as solvent-free, catalytic, reactants immobilized on a solid support, one-pot synthesis, and microwave irradiation.

Simulation and Analysis of Anodized Aluminum Oxide Membrane Degradation.

Microelectromechanical systems (MEMS)-based filter with microchannels enables the removal of various microorganisms, including viruses and bacteria, from fluids. Membranes with porous channels can be used as filtration interfaces in MEMS hemofilters or mini-dialyzers. The main problems associated with the filtration process are optimization of membrane geometry and fouling.

Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane.

Microfluidic devices have gained subsequent attention due to their controlled manipulation of fluid for various biomedical applications. These devices can be used to study the behavior of fluid under several micrometer ranges within the channel. The major applications are the filtration of fluid, blood filtration and bio-medical analysis.

Temporomandibular Disorders among Dental Students in Pakistan: Assessment of Prevalence, Severity, and Associated Factors Based on Questionnaire.

Objective: To evaluate the prevalence, severity, and associated factors of temporomandibular disorder (TMD) among dental students.

Methods: This cross-sectional study was performed on undergraduate dental students from four dental colleges in Punjab, Pakistan. Fonseca's questionnaire was used to measure the prevalence and severity of the TMD among the study participants.

Modeling the Interaction of Coronavirus Membrane Phospholipids with Photocatalitically Active Titanium Dioxide.

The outbreak of viral infectious diseases urges airborne droplet and surface disinfection strategies, which may rely on photocatalytic semiconductors. A lipid bilayer membrane generally encloses coronaviruses and promotes the anchoring on the semiconductor surface, where, upon photon absorption, electron-hole pairs are produced, which can react with adsorbed oxygen-containing species and lead to the formation of reactive oxygen species (ROSs). The photogenerated ROSs may support the disruptive oxidation of the lipidic membrane and pathogen death.

Triboelectric and Piezoelectric Nanogenerators for Self-Powered Healthcare Monitoring Devices: Operating Principles, Challenges, and Perspectives.

The internet of medical things (IoMT) is used for the acquisition, processing, transmission, and storage of medical data of patients. The medical information of each patient can be monitored by hospitals, family members, or medical centers, providing real-time data on the health condition of patients. However, the IoMT requires monitoring healthcare devices with features such as being lightweight, having a long lifetime, wearability, flexibility, safe behavior, and a stable electrical performance.

Computational Modeling of Chromatin Fiber to Characterize Its Organization Using Angle-Resolved Scattering of Circularly Polarized Light.

Understanding the structural organization of chromatin is essential to comprehend the gene functions. The chromatin organization changes in the cell cycle, and it conforms to various compaction levels. We investigated a chromatin solenoid model with nucleosomes shaped as cylindrical units arranged in a helical array.

Big Data acquired by Internet of Things-enabled industrial multichannel wireless sensors networks for active monitoring and control in the smart grid Industry 4.0.

Smart Grid Industry 4.0 (SGI4.0) defines a new paradigm to provide high-quality electricity at a low cost by reacting quickly and effectively to changing energy demands in the highly volatile global markets.

Dynamics of water conveying zinc oxide through divergent-convergent channels with the effect of nanoparticles shape when Joule dissipation are significant.

Aim Of Study: The shape effects of nanoparticles are very significant in fluid flow and heat transfer. In this paper, we discuss the effects of nanoparticles shape in nanofluid flow between divergent-convergent channels theoretically. In this present study, various shapes of nanoparticles, namely sphere, column and lamina in zinc oxide-water nanofluid are used.

Isolation, characterization and prevention of various microbial strains in NIC unit and PIC unit.

The health of the hospital associated persons, particularly those dealing directly with insertion of devices, are serious cause of concern for hospitals. In this study, the most prevalent organism on the surface of medical devices in PICU were CoNS (16.66%) and Staphylococcus aureus (16.

Fuzzy-Based Approach Using IoT Devices for Smart Home to Assist Blind People for Navigation.

The demand of devices for safe mobility of blind people is increasing with advancement in wireless communication. Artificial intelligent devices with multiple input and output methods are used for reliable data estimation based on maximum probability. A model of a smart home for safe and robust mobility of blind people has been proposed.

Population Modelling of Dexmedetomidine Pharmacokinetics and Haemodynamic Effects After Intravenous and Subcutaneous Administration.

Background And Objective: Dexmedetomidine is a potent agonist of α-adrenoceptors causing dose-dependent sedation in humans. Intravenous dexmedetomidine is commonly used perioperatively, but an extravascular route of administration would be favoured in palliative care. Subcutaneous infusions provide desired therapeutic plasma concentrations with fewer unwanted effects as compared with intravenous dosing.

Prioritization of Information Security Controls through Fuzzy AHP for Cloud Computing Networks and Wireless Sensor Networks.

With the advent of cloud computing and wireless sensor networks, the number of cyberattacks has rapidly increased. Therefore, the proportionate security of networks has become a challenge for organizations. Information security advisors of organizations face difficult and complex decisions in the evaluation and selection of information security controls that permit the defense of their resources and assets.

QoSRP: A Cross-layer QoS Channel-Aware Routing Protocol for the Internet of Underwater Acoustic Sensor Networks.

Quality of service (QoS)-aware data gathering in static-channel based underwater wireless sensor networks (UWSNs) is severely limited due to location and time-dependent acoustic channel communication characteristics. This paper proposes a novel cross-layer QoS-aware multichannel routing protocol called QoSRP for the internet of UWSNs-based time-critical marine monitoring applications. The proposed QoSRP scheme considers the unique characteristics of the acoustic communication in highly dynamic network topology during gathering and relaying events data towards the sink.

Comparison of physiological responses of Arabian striped hyaena () to effective immobilisations with ketamine-medetomidine and ketamine-xylazine in (semi-) captive conditions.

Chemical immobilisation is an integral component for the conservation of wild animals and can be stressful if proper protocols are not administered. References on the immobilisation of Arabian striped hyaena () are scarce. The current study was designed to evaluate the physiological and clinical responses of Arabian striped hyaena, immobilised with ketamine-medetomidine (KM) and ketamine-xylazine (KX); and to compare immobilisation effectiveness of the two combinations in a cross-sectional clinical study.

Sinusoidal Microchannel with Descending Curves for Varicose Veins Implantation.

Approximately 26% of adult people, mostly females, are affected by varicose veins in old age. It is a common reason for distress, loss of efficiency, and worsening living conditions. Several traditional treatment techniques (sclerotherapy and foam sclerotherapy of large veins, laser surgeries and radiofrequency ablation, vein ligation and stripping, ambulatory phlebectomy, and endoscopic vein surgery) have failed to handle this disease effectively.

Semimechanistic Population Pharmacokinetic Model to Predict the Drug-Drug Interaction Between S-ketamine and Ticlopidine in Healthy Human Volunteers.

Low-dose oral S-ketamine is increasingly used in chronic pain therapy, but extensive cytochrome P450 (CYP) mediated metabolism makes it prone to pharmacokinetic drug-drug interactions (DDIs). In our study, concentration-time data from five studies were used to develop a semimechanistic model that describes the ticlopidine-mediated inhibition of S-ketamine biotransformation. A mechanistic model was implemented to account for reversible and time-dependent hepatic CYP2B6 inactivation by ticlopidine, which causes elevated S-ketamine exposure in vivo.

Simulation, Fabrication and Analysis of Silver Based Ascending Sinusoidal Microchannel (ASMC) for Implant of Varicose Veins.

Bioengineered veins can benefit humans needing bypass surgery, dialysis, and now, in the treatment of varicose veins. The implant of this vein in varicose veins has significant advantages over the conventional treatment methods. Deep vein thrombosis (DVT), vein patch repair, pulmonary embolus, and tissue-damaging problems can be solved with this implant.

Levels of Organotin Compounds in Selected Fish Species from the Arabian Gulf.

In the present work, data on the levels of hazardous Organotin compounds in eight commercially important fish species, caught from Arabian Gulf, has been reported. Highest levels of tributyltin (TBT) (98.5 ng/g dry weight) were detected in Epinephelus Tauvina whereas minimum (43.

Levels of heavy metals in popular cigarette brands and exposure to these metals via smoking.

The levels of selected heavy metals in popular cigarette brands sold and/or produced in Saudi Arabia were determined by graphite furnace-atomic absorption spectrometry (GFAAS). Average concentrations of Cadmium and Lead in different cigarette brands were 1.81 and 2.

Polycyclic aromatic hydrocarbons (PAHs) in vegetables and fruits produced in Saudi Arabia.

Popular varieties of vegetables were collected from major cities of Saudi Arabia and analyzed for polycyclic aromatic hydrocarbons (PAH) contents. Eight important PAH congeners were analyzed. Total PAH contents of the root vegetables like potato and carrot showed higher values (11 μg kg(-1)), whereas turnip showed relatively lower contents at 9.

Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications.

Micro Electromechanical Systems (MEMS) based microfluidic devices have gained popularity in biomedicine field over the last few years. In this paper, a comprehensive overview of microfluidic devices such as micropumps and microneedles has been presented for biomedical applications. The aim of this paper is to present the major features and issues related to micropumps and microneedles, e.