Publications by authors named "Muhammad Umar Mian"

Article Synopsis
  • * Results showed that IVUS guidance significantly reduced the risk of major adverse cardiac events (MACE) and stent thrombosis compared to angiography guidance, while also favoring better outcomes in secondary measures like cardiac mortality and myocardial infarction.
  • * Although IVUS showed advantages in reducing the need for repeat procedures, factors like cost-effectiveness and the requirement for specialized training must be addressed for its broader implementation in clinical settings.
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  • Neurosarcoidosis is a rare form of sarcoidosis that complicates the nervous system, making it challenging to diagnose and treat due to its diverse symptoms.
  • A case of a 67-year-old man showed signs like altered sensorium and weight loss, leading to tests that eventually diagnosed him with neurosarcoidosis based on imaging and biopsy results.
  • Treatment with prednisolone and methotrexate resulted in significant improvement, illustrating the need for a multidisciplinary approach in handling such complex cases.
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  • * A review of various studies found that gabapentinoids (like gabapentin and pregabalin) and tricyclic antidepressants (like amitriptyline) are effective for managing neuropathic pain by targeting neurotransmitters.
  • * While selective serotonin reuptake inhibitors (SSRIs) are less effective for this type of pain, cannabinoids showed promise with mild side effects; opioids are generally a last resort due to their risks.
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Acute coronary syndrome (ACS) remains a leading cause of morbidity and mortality worldwide. Statins, particularly atorvastatin, and rosuvastatin, are crucial in managing cholesterol levels and reducing cardiovascular risk in ACS patients. However, direct comparative studies between these two statins are limited.

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We present a case of invasive pulmonary aspergillosis in an immunocompetent young female. An 18-year-old female presented with symptoms of a left-sided middle cerebral artery (MCA) stroke with right arm weakness and aphasia. Computed tomography (CT) brain confirmed the diagnosis of stroke.

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The coronary sinus reducer (CSR), a minimally invasive device, has emerged as a promising alternative for improving myocardial perfusion in these patients. This meta-analysis evaluated the effectiveness of CSR implantation in patients with refractory angina. A comprehensive search of PubMed, EMBASE, and Web of Science databases identified 10 relevant studies with a pooled sample size of 799 patients.

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