Publications by authors named "Muhammad Taha Hagar"

Rationale And Objectives: The purpose of this study was to explore intra-individual differences in pericoronary adipose tissue (PCAT) fat attenuation index (FAI) between photon-counting detector (PCD)- and energy-integrating detector (EID)-CT.

Material And Methods: Patients were prospectively enrolled for a PCD-CT research scan within 30 days of EID-CT. Both acquisitions were reconstructed using a Qr36 kernel at 0.

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Article Synopsis
  • The text reviews advancements in dual-source photon-counting detector CT (PCD-CT) technology for cardiovascular imaging since its approval in 2021, focusing on innovative applications and research.
  • A structured literature review identified studies that highlighted benefits such as improved image quality, better radiation dose management, and feasibility for non-invasive diagnostics in diverse patient populations.
  • Despite these advantages, there are ongoing challenges like high costs, extensive data handling, slower reconstruction times, and the need for more clinical evidence to validate the technology's superiority.
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Purpose: The study aimed to assess the feasibility and image quality of dual-source photon-counting detector computed tomography (PCD-CT) in evaluating small-sized coronary artery stents with respect to different acquisition modes in a phantom model.

Methods: Utilizing a phantom setup mimicking the average patient's water-equivalent diameter, we examined six distinct coronary stents inflated in a silicon tube, with stent sizes ranging from 2.0 to 3.

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Purpose: To evaluate the feasibility of CT angiography-derived fractional flow reserve (CT-FFR) calculations on ultrahigh-resolution (UHR) photon-counting detector (PCD)-CT series and to intra-individually compare the results with energy-integrating (EID)-CT measurements.

Method: Prospective patients with calcified plaques detected on EID-CT between April 1st, 2023 and January 31st, 2024 were recruited for a UHR CCTA on PCD-CT within 30 days. PCD-CT was performed using the same or a lower CT dose index and an equivalent volume of contrast media.

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Article Synopsis
  • The introduction of photon-counting detector computed tomography (PCD-CT) represents a significant advancement in cardiac imaging technology since its market launch in 2021.
  • This review examines the benefits of PCD-CT, highlighting improvements in image quality, spatial resolution, contrast-to-noise ratio, reduced artifacts, and lower radiation exposure.
  • Despite promising early results, researchers are still evaluating how PCD-CT's advantages will influence future clinical guidelines for cardiac imaging.
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Background CT-derived fractional flow reserve (CT-FFR) and dynamic CT myocardial perfusion imaging enhance the specificity of coronary CT angiography (CCTA) for ruling out coronary artery disease (CAD). However, evidence on comparative diagnostic value remains scarce. Purpose To compare the diagnostic accuracy of CCTA plus CT-FFR, CCTA plus CT perfusion, and sequential CCTA plus CT-FFR and CT perfusion for detecting hemodynamically relevant CAD with that of invasive angiography.

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Purpose: To investigate the value of photon-counting detector CT (PCD-CT) derived virtual non-contrast (VNC) reconstructions to identify renal cysts in comparison with conventional dual-energy integrating detector (DE EID) CT-derived VNC reconstructions.

Material And Methods: We prospectively enrolled consecutive patients with simple renal cysts (Bosniak classification-Version 2019, density ≤ 20 HU and/or enhancement ≤ 20 HU) who underwent multiphase (non-contrast, arterial, portal venous phase) PCD-CT and for whom non-contrast and portal venous phase DE EID-CT was available. Subsequently, VNC reconstructions were calculated for all contrast phases and density as well as contrast enhancement within the cysts were measured and compared.

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  • This study looked at two types of CT scans, UHR-CTA and HPS-CTA, to see which one is better for planning heart valve surgery in patients with serious heart issues.
  • It involved 64 older patients and found that HPS-CTA used less radiation but UHR-CTA provided clearer images of the heart.
  • Both scans gave similar measurements for sizing the new heart valves, but when the images from HPS-CTA were not as good, doctors sometimes suggested different valve sizes.
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Purpose: To determine the diagnostic accuracy of volumetric interpolated breath-hold examination sequences with fat suppression in Dixon technique (VIBE-Dixon) for cardiac thrombus detection.

Method: From our clinical database, we retrospectively identified consecutive patients between 2014 and 2022 who had definite diagnosis or exclusion of cardiac thrombus confirmed by an independent adjudication committee, serving as the reference standard. All patients received 2D-Cine plus 2D-Late-Gadolinium-Enhancement (Cine + LGE) and VIBE-Dixon sequences.

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Objectives: To determine the diagnostic accuracy of ultra-high-resolution photon-counting detector CT angiography (UHR PCD-CTA) for evaluating coronary stent patency compared to invasive coronary angiography (ICA).

Methods: Consecutive, clinically referred patients with prior coronary stent implantation were prospectively enrolled between August 2022 and March 2023 and underwent UHR PCD-CTA (collimation, 120 × 0.2 mm).

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Background: Photon-counting detector computed tomography (PCD-CT) is a promising new technology with the potential to fundamentally change workflows in the daily routine and provide new quantitative imaging information to improve clinical decision-making and patient management.

Method: The contents of this review are based on an unrestricted literature search of PubMed and Google Scholar using the search terms "photon-counting CT", "photon-counting detector", "spectral CT", "computed tomography" as well as on the authors' own experience.

Results: The fundamental difference with respect to the currently established energy-integrating CT detectors is that PCD-CT allows for the counting of every single photon at the detector level.

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Article Synopsis
  • Accurate small vessel stent visualization using CT is difficult, but photon-counting CT (PCD-CT) shows promise in improving this assessment compared to traditional energy-integrating CT (EID-CT).
  • A study involved scanning 12 water-contrast agent filled stents with PCD-CT and EID-CT, evaluating image quality subjectively with radiologists and objectively through intensity profile calculations.
  • PCD-CT produced better overall reading scores and higher diagnostic confidence, suggesting it may enhance small vessel stent imaging effectiveness, though further research is needed for clinical application.
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Aims: To determine the conditions under which early hypoattenuated leaflet thickening (HALT) after transcatheter aortic valve implantation (TAVI) becomes haemodynamically relevant.

Methods And Results: The study included 100 patients (age: 81.5 ± 5.

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Background: This study investigates whether the scan length adjustment of prospectively ECG-triggered coronary CT angiography (CCTA) using calcium-scoring CT (CAS-CT) images can reduce overall radiation doses.

Methods: A retrospective analysis was conducted on 182 patients who underwent CAS-CT and prospectively ECG-triggered CCTA using a second-generation Dual-Source CT scanner. CCTA planning was based on CAS-CT images, for which simulated scout view planning was performed for comparison.

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Background Recently introduced photon-counting CT may improve noninvasive assessment of patients with high risk for coronary artery disease (CAD). Purpose To determine the diagnostic accuracy of ultrahigh-resolution (UHR) coronary CT angiography (CCTA) in the detection of CAD compared with the reference standard of invasive coronary angiography (ICA). Materials and Methods In this prospective study, participants with severe aortic valve stenosis and clinically indicated CT for transcatheter aortic valve replacement planning were consecutively enrolled from August 2022 to February 2023.

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Background: Kidney transplantations are increasing due to demographic changes and are the treatment of choice for end-stage renal disease. Non-vascular and vascular complications may occur in the early phase after transplantation and at later stages. Overall postoperative complications after renal transplantations occur in approximately 12 % to 25 % of renal transplant patients.

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The aim of this paper is to evaluate the diagnostic image quality of spectral dual-source photon-counting detector coronary computed tomography angiography (PCD-CCTA) for coronary artery disease in a multicenter study. The image quality (IQ), assessability, contrast-to-noise ratio (CNR), Agatston score, and radiation exposure were measured. Stenoses were quantified and compared with invasive coronary angiography, if available.

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Background: Aim of this study was to report and to identify risk factors for distal aortic failure following aortic arch replacement via the frozen elephant trunk (FET) procedure.

Methods: One hundred eighty-six consecutive patients underwent the FET procedure for acute and chronic aortic dissection. Our cohort was divided into patients with and without distal aortic failure.

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Background: Coronary CT angiography (cCTA) is a class 1 recommendation in the current guidelines by the European Society of Cardiology (ESC) for excluding significant coronary artery stenosis. To achieve optimal image quality at a low radiation dose, the imaging physician may choose different acquisition modes. Therefore, the consensus guidelines by the Society of Cardiovascular Computed Tomography (SCCT) provide helpful guidance for this procedure.

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Objectives: To evaluate a systolic ECG-gated high-pitch aortoiliac computed tomography (CT) angiography for planning transcatheter aortic valve implantation (TAVI).

Methods: Patients referred for TAVI underwent a combined CT imaging with retrospective, multiphasic ECG-gating of the heart and systolic ECG-gated high-pitch aortoiliac CT angiography. Consecutive patients were retrospectively included in this study group.

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