Most of the countries in the world are affected by the coronavirus epidemic that put people in danger, with many infected cases and deaths. The crowding factor plays a significant role in the transmission of coronavirus disease. On the other hand, the vaccines of the covid-19 played a decisive role in the control of coronavirus infection.
View Article and Find Full Text PDFThis article suggests a fourth-order numerical approach for solving ordinary differential equations (ODEs) that are both linear and nonlinear. The suggested scheme is an explicit predictor-corrector scheme. For linear ODE, the proposed numerical scheme's stability area is discovered.
View Article and Find Full Text PDFThis research deals with formulating a multi-species eco-epidemiological mathematical model when the interacting species compete for the same food sources and the prey species have some infection. It is assumed that infection does not spread vertically. Infectious diseases severely affect the population dynamics of prey and predator.
View Article and Find Full Text PDFFluoro-perovskites compounds based on the Tl element TlMF (M = Au, Ga) were examined computationally, and their different aspects, studied utilizing TB-mBJ potential approximations, can be used for the generation of energy because of their ever-increasing power conversion efficiency. Birch Murnaghan's graph and tolerance factor show that these composites are structurally cubic and stable. The optimum volume of the compounds corresponding to the optimum energies and the optimized lattice constants were computed.
View Article and Find Full Text PDFIran J Sci Technol Trans A Sci
September 2021
In this contribution, a first-order time scheme is proposed for finding solutions to partial differential equations (PDEs). A mathematical model of the COVID-19 epidemic is modified where the recovery rate of exposed individuals is also considered. The linear stability of the equilibrium states for the modified COVID-19 model is given by finding its Jacobian and applying Routh-Hurwitz criteria on characteristic polynomial.
View Article and Find Full Text PDFAn explicit unconditionally stable scheme is proposed for solving time-dependent partial differential equations. The application of the proposed scheme is given to solve the COVID-19 epidemic model. This scheme is first-order accurate in time and second-order accurate in space and provides the conditions to get a positive solution for the considered type of epidemic model.
View Article and Find Full Text PDFThe current effort is devoted to investigating and exploring the stochastic nonlinear mathematical pandemic model to describe the dynamics of the novel coronavirus. The model adopts the form of a nonlinear stochastic susceptible-infected-treated-recovered system, and we investigate the stochastic reproduction dynamics, both analytically and numerically. We applied different standard and nonstandard computational numerical methods for the solution of the stochastic system.
View Article and Find Full Text PDFBackground: Latent HIV-1 is a major hurdle in obtaining HIV-1 sustained virological remission (SVR). Here we explored histone deacetylation inhibition property of nicotinamide (NAM; n=17) for the first time in comparison to a combination of methyltransferase inhibitors (MTIs; Chaetocin and BIX01294; n=25) to reactivate latent HIV ex vivo in CD8-depleted PBMCs from antiretroviral treated aviremic individuals.
Results: NAM reactivated HIV-1 from 13/17 (76.
This manuscript discusses a competitive analysis of stochastic influenza model with constant vaccination strategy. The stochastic influenza model is comparatively more pragmatic versus the deterministic influenza model. The effect of influenza generation number holds in the stochastic model.
View Article and Find Full Text PDFThis study is an attempt to explain a reliable numerical analysis of a stochastic HIV/AIDS model in a two-sex population considering counselling and antiretroviral therapy (ART). The authors are comparing the solutions of the stochastic and deterministic HIV/AIDS epidemic model. Here, an endeavour has been made to explain the stochastic HIV/AIDS epidemic model is comparatively more pragmatic in contrast with the deterministic HIV/AIDS epidemic model.
View Article and Find Full Text PDFTrial Design: Open-label, randomised, controlled, pilot proof-of-concept clinical trial.
Methods: Participants: Antiretroviral naïve adult males with CD4 count ≥350cells/mm.
Interventions: Patients were randomised to receive thalidomide 200mg QD for 3weeks (Thalidomide group) or not (Control group) and followed for 48weeks.
HIV-1 entry into target cells influences several aspects of HIV-1 pathogenesis, including viral tropism, HIV-1 transmission and disease progression, and response to entry inhibitors. The evolution from CCR5- to CXCR4-using strains in a given human host is still unpredictable. Here we analyzed timing and predictors for coreceptor evolution among recently HIV-1-infected individuals.
View Article and Find Full Text PDFItajaí is a port city in southern Brazil with one of the highest incidence and mortality rates from AIDS in the country. The prevalence and incidence of HIV infection were investigated in 1085 of 3196 new HIV-1 infection cases evaluated in the counseling and testing center of Itajaí from January 2002 to August 2008. Recent infections were assessed using the BED™, and pol region sequencing was performed in 76 samples.
View Article and Find Full Text PDFGenotropism was determined in 608 Brazilian samples collected in dried blood spots using Polyethersulfone collection cards. Patients were infected by subtype B (88.8%), F (5.
View Article and Find Full Text PDFHereditary leukonychia or porcelain nails is a nail dystrophy characterized by whitening of the nail plates in all nails of the hands and feet. It may exhibit an autosomal recessive or autosomal dominant pattern of inheritance. Mutations in the gene PLCD1 have been reported to underlie hereditary leukonychia.
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