Publications by authors named "Muhammad Najib"

Background And Importance: Fusiform middle cerebral artery (MCA) bifurcation aneurysms can be challenging to treat with standard endovascular or microsurgical techniques. The in situ side-to-side bypass technique represents an elegant revascularization option for these aneurysms when trapping becomes necessary.

Clinical Presentation: A man in his 50s presented for evaluation of an incidentally found fusiform, 10 mm, right MCA bifurcation aneurysm with involvement of both the inferior and superior M2 trunks.

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Study Design: A retrospective database study.

Objective: To compare complications and costs associated with endoscopic and open lumbar decompression on a large scale.

Background: Though open lumbar decompression is considered the gold standard, endoscopic procedures are on the rise.

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Brain arteriovenous malformations (AVMs) are vascular lesions characterized by abnormal connections between parenchymal arteries and veins, bypassing a capillary bed, and forming a nidus. Brain AVMs are consequential as they are prone to rupture and associated with significant morbidity. They can broadly be subdivided into hereditary vs.

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  • A new methodology has been developed for predicting how fast different faces of single-faceted crystals dissolve in a solvent, differing from previous models by considering uneven wetting on crystal surfaces.
  • The method builds on an earlier binding energy model that focused solely on solid-state interactions, now incorporating how the solvent interacts with each crystal surface.
  • The model shows strong agreement with experimental data for ibuprofen and furosemide, paving the way for more accurate predictions of dissolution rates in various solvents.
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  • The text discusses a case of urgent carotid endarterectomy (CEA) and distal thrombectomy in a patient with multiple strokes and significant carotid artery occlusion.
  • The patient presented with symptoms like facial droop and aphasia, leading to imaging studies that revealed severe blockages in the left carotid artery and middle cerebral artery (MCA).
  • Despite initial attempts at thrombectomy being unsuccessful, the surgeons converted to open CEA, successfully achieved blood flow restoration to the MCA, and delivered reperfusion to improve the patient's condition.
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Persistent trigeminal artery (PTA) is the most common remnant of the primitive carotid-vertebrobasilar anastomoses, which typically form and obliterate during the early stages of human embryonic development. While PTA can be non-pathologic and is usually an incidental finding, it is also associated with various other vascular abnormalities, such as arteriovenous malformations and fistulae, but most commonly cerebral aneurysms. In these cases, aneurysms are usually reported in the anterior cerebral circulation or in the PTA trunk itself; to date, only one report exists of an associated aneurysm in the posterior circulation (basilar artery).

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Objective: Surgery remains the first line treatment for meningiomas and can benefit from fluorescence-guided surgical techniques such as second-window indocyanine green (SWIG). In the current study, we compared the use of the standard SWIG dose of 5.0 mg/kg relative to 2.

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Study Design: This study was a multicenter retrospective analysis of cervical spine gunshot wound (GSW) patients.

Objective: The present study was conducted to evaluate the management and outcomes of vascular injuries following GSW involving the cervical spine.

Summary Of Background Data: Gunshot wounds (GSW) injuring the cervical spine are associated with high rates of vascular injury.

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  • * It was found that using ultrasonic vibrations during welding can lower the welding load and positively affect the microstructure and joint properties, particularly when combined with a lower heat input.
  • * The research suggests that faster welding speeds (at least 220 mm/min) improve joint quality, with ultrasonic vibration having a more significant impact under these conditions despite a minor influence on irregular intermetallic compounds formed in the weld.
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  • SWIG is a new imaging technique that uses near-infrared light with the dye indocyanine green (ICG) to help surgeons better visualize and remove cranial nerve schwannomas while protecting nearby nerves.
  • In a study involving three patients with different types of schwannomas, the use of SWIG allowed for successful tumor resections and significant symptom relief after a follow-up period of six months.
  • The results highlight the effectiveness of ICG when infused 24 hours before surgery and indicate the potential for SWIG to be applied to various types of brain tumors in future research.
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  • The study examines the financial trends of three diagnostic tests for cerebrovascular disease—DSA, CTA, and MRA—amid rising life expectancy and changing Medicare payment structures.
  • Over 1.5 million procedures were analyzed from 2013 to 2020, revealing a decline in Medicare reimbursements and procedural volume for DSA and MRA, while CTA volume slightly increased.
  • Key findings indicate a significant drop in reimbursements for angiograms and MRAs, with the overall trend showing a need for neurointerventional practices to adapt to these financial challenges.
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Objective: The authors designed a low-profile device for reliable ventricular access and prospectively studied its safety, efficacy, and accuracy at a large academic center.

Methods: A novel device for ventricular entry, the Device for Intraventricular Entry (DIVE) guide, was designed and created by the first and senior authors. Fifty patients undergoing external ventricular drainage (EVD) or shunt placement were prospectively enrolled for DIVE-assisted catheter placement at a single academic center.

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Background: Historically, the transfemoral approach (TFA) has been the most common access site for cerebral intraoperative angiography (IOA). However, in line with trends in cardiac interventional vascular access preferences, the transradial approach (TRA) and transulnar approach (TUA) have been gaining popularity owing to favorable safety and patient satisfaction outcomes.

Objective: To compare the efficacy and safety of TRA/TUA and TFA for cerebral and spinal IOA at an institutional level over a 6-year period.

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Background: Transradial approach for neuroangiography is becoming increasingly popular because of the advantages demonstrated by interventional cardiology. Many advantages of radial access could be applied to intraoperative angiography.

Objective: To report our institutional experience with transradial and transulnar intraoperative angiography, and evaluate its safety and feasibility.

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A 72-year-old female with a history of hypertension and hyperlipidemia presented to the emergency department from an outside hospital with acute confusion and global amnesia immediately following cervical epidural steroid injection with fluoroscopic guidance for radiculopathy relief. On exam, she was oriented to self, but disoriented to place and situation. Otherwise, she was neurologically intact with no deficits.

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Significance: This third biennial intraoperative molecular imaging (IMI) conference shows how optical contrast agents have been applied to develop clinically significant endpoints that improve precision cancer surgery.

Aim: National and international experts on IMI presented ongoing clinical trials in cancer surgery and preclinical work. Previously known dyes (with broader applications), new dyes, novel nonfluorescence-based imaging techniques, pediatric dyes, and normal tissue dyes were discussed.

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Article Synopsis
  • - The study reviews the effectiveness and safety of intraoperative angiography (IOA) during neurosurgery with patients positioned prone, three-quarters prone, and park-bench.
  • - A total of 26 studies and 32 cases from one institution were analyzed, showing a 98% success rate for IOA and a 1% complication rate, with no reported deaths.
  • - The results indicate that while IOA is both feasible and generally safe, there is a significant rate of surgical adjustments needed afterwards, suggesting it can beneficially impact patient outcomes in vascular neurosurgery.
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Background: Intraoperative DSA is used to confirm complete obliteration of neurovascular pathologies. For spinal neurovascular lesions, femoral access can be challenging given the need to flip the patient after sheath placement. Similarly, radial access can be complicated by arch navigation difficulties.

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Three dinuclear dysprosium(III) complexes, [Dy L (O CPh) ]⋅2 MeOH (1), [Dy L {(2-NO )O CPh} ] (2), and [Dy L {(2-OH)O CPh} ]⋅MeOH⋅MeCN (3) (H L=N ,N -bis(4-chlorosalicyladehyde)diethylenetriamine), have been synthesized and structurally characterized. Complexes 1-3 possess similar Ln cores and differ in substituents at the benzyl rings of benzoates. Direct current (dc) magnetic susceptibility studies in the 2-300 K range showed weak antiferromagnetic interactions between two dysprosium(III) ions in 1-3.

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