Ataxia telangiectasia is a rare autosomal recessive condition which develops due to a mutation in the ataxia telangiectasia mutated gene (ATM gene). As a result of this mutation, the ability of the DNA to undergo repair is undermined. The resulting cellular demise is responsible for the diverse presentation of the clinical condition.
View Article and Find Full Text PDFProstate cancer is the most common malignancy among males worldwide, and is the second leading cause of cancer death among men in United States. According to GLOBOCAN (2012), an estimated 1.1 million new cases and 307,000 deaths were reported in 2012.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
February 2016
Background: The effects of diet on epidemiology of prostate cancer are inconclusive. Therefore a hospital- based, case-control study was conducted in a rural population of Faisalabad, Pakistan, to examine the impact of dietary factors on risk of cancer development.
Materials And Methods: This study was based on 102 confirmed cases of prostate cancer and 204 normal controls.
Asian Pac J Cancer Prev
September 2015
Background: Prostate cancer is the third most commonly diagnosed cancer among males in Pakistan but very little is known about risk factors among the Pakistani population. Therefore a hospital-based, case-control study was carried out in Faisalabad to identify potential risk factors.
Materials And Methods: This study was based on 140 prostate cancer cases and 280 normal controls.