Prevalence and Possible Predictors of Helicobacter Pylori Infection Among Adult Patients with Sickle Cell Disease in Ahmadu Bello University Teaching Hospital North-West, Nigeria.

Background: Helicobacter Pylori infection occurs worldwide. Patients with Sickle Cell Disease (SCD) may present with abdominal symptoms due to different pathophysiological mechanisms. SCD patients are predisposed to infections due to immune deficiency, abdominal symptoms like dyspepsia and recurrent abdominal pain have been associated with infection.

[ANALYSIS AND COMPARISON OF SERUM LIPID PROFILE IN PATIENTS WITH DIABETIC MELLITUS AND HYPERTENSION IN A TERTIARY HEALTH CENTRE IN NORTH WEST NIGERIA].

Background: Serum Lipid profile is an important biochemical parameter that can be used as a marker of adverse cardiovascular events.

Aims And Objectives: This study aim to analyze and compare serum lipid profile among hypertensive and diabetic patients.

Methods: Serum lipid profile of 172 and 142 patients with diagnosis of hypertension and diabetes mellitus respectively seen over a 4year period were retrieved from the electronic data base of chemical pathology department of Barau Dikko Teaching Hopital, Kaduna.

Demographic Profile and Etiology of Hepatocellular Carcinoma in Zaria, Northern Nigeria.

Background: HCC is a common cancer worldwide and one of the leading causes of cancer death. This aim of this study is to determine the age and gender characteristics of the HCC patients in our center and to determine the contribution of viral hepatitis (B and C) and alcohol to the etiology of HCC among our patients.

Methodology: This is a retrospective study of HCC patients seen at the gastroenterology unit of ABUTH between April 2015 and September 2018.

Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin.

Evasion of apoptosis is associated with treatment resistance and metastasis in colorectal cancer (CRC). Various cellular processes are associated with evasion of apoptosis. These include overexpression of pro-apoptotic proteins (including p53 and PD-L1), anti-apoptotic proteins (BIRC7/Livin and Bcl-2), chemokine receptors (including DARC), and dysregulation of DNA mismatch repair proteins (including MSH2 and PMS2).

Patterns of Early-Onset Colorectal Cancer Among Nigerians and African Americans.

Purpose: Colorectal cancer (CRC) incidence rates are increasing among individuals < 50 years of age (early-onset CRC) globally with causes unknown. Racial/ethnic disparities in early-onset CRC have also grown more pronounced, because Black individuals have higher early-onset CRC incidence and poorer survival compared with White individuals. We describe the prevalence and burden of early-onset CRC among Africans in Nigeria and African Americans (AAs) in the United States.