Publications by authors named "Muhammad Khurram Mahmood"
Article Synopsis
- The study aimed to examine the levels of Cyclin D1 and Ki-67 in both primary oral squamous cell carcinoma (OSCC) and its metastatic forms, focusing on various histological grades.
- Thirty samples were analyzed, revealing that primary OSCC patients had an average age of about 53, while those with metastasis were around 61, with males being more affected and the tongue being the most common site for tumors.
- Results showed a significant difference in Cyclin D1 expression between primary and metastatic OSCC, suggesting it may be a valuable marker for determining the aggressiveness and potential metastasis of the disease.
Frequency of Delayed Diagnosis of Oral Squamous Cell Carcinoma in Pakistan.
Asian Pac J Cancer Prev
November 2016
Objectives: To determine the frequency of delayed diagnosis of oral squamous cell carcinoma in our setup; highlighting factors responsible for any delay and their possible relevance to demographic and diagnostic features. Methods: This cross sectional study of six months duration was conducted in the Oral and Maxillofacial Surgery Department of the Armed Forces Institute of Dentistry, Rawalpindi, Pakistan. A total of 246 patients, both male and female, having a biopsy proven definitive diagnosis of OSCC were included using a consecutive sampling technique.
View Article and Find Full Text PDFPurpose: To determine the biological behaviour of common odontogenic cystic lesions by analysing and comparing bcl-2 expression amongst them.
Materials And Methods: Our study covered 90 formalin fixed paraffin embedded tissue samples: 26 primary cases each of radicular cysts (RC), dentigerous cysts (DC) and odontogenic keratocysts (OKC) and 12 of recurrent OKCs. Bcl-2 expression was analysed immunohistochemically and data analysis was accomplished using SPSS version 17.
Background: The purpose of the study was to analyse the clinicopathological spectrum of benign and malignant odontogenic tumours (OT) in Pakistan.
Materials And Methods: This retrospective study was carried out at the Armed Forces Institute of Pathology (AFIP) Rawalpindi. Seven years archival records of histologically diagnosed odontogenic tumours, both benign and malignant, were collected and the lesions re-diagnosed histologically in accordance with the WHO classification of head and neck tumours (2005).