Metabolite Biomarkers for Early Detection of Pancreatic Ductal Adenocarcinoma: A Systematic Review.

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a poor prognosis. This poor prognosis is largely attributed to a late-stage diagnosis. Recent advancements in metabolomics have emerged as a promising avenue for biomarker discovery in PDAC.

Prevalence, Incidence and Risk Factors of White Spot Lesions Associated With Orthodontic Treatment - A Systematic Review and Meta-Analysis.

The primary objective was to systematically assess the prevalence, incidence and risk factors of WSLs with orthodontic treatment. The secondary objective was to compare the prevalence of WSLs between conventional fixed appliances (CFA) and other appliances, as well as with no treatment. PubMed, Scopus, Web of Science, LILACs, Virtual Health Library and Cochrane CENTRAL were searched.

Arbuscular Mycorrhizal Fungi-Assisted Phytoremediation: A Promising Strategy for Cadmium-Contaminated Soils.

Arbuscular mycorrhizal fungi (AMF) have been shown to play a major role in regulating the accumulation, transport, and toxicity of cadmium (Cd) in plant tissues. This review aims to highlight the current understanding of the mechanisms by which AMF alleviate Cd toxicity in plants. Cd accumulation in agricultural soils has become an increasing global concern due to industrial activities and the use of phosphatic fertilizers.

Genetic analysis of chlorantraniliprole resistance in the non-target bio-control agent Trichogrammachilonis.

Trichogramma chilonis (Ishii) (Hymenoptera: Trichogrammatidae), a widely used egg parasitoid of lepidopteran pests in various crops, has developed very high levels of resistance when treated with chlorantraniliprole under laboratory conditions. This study assessed and characterized its mode of inheritance, degree of dominance, realized heritability (h), and cross-resistance. Toxicity bioassays were performed on T.

Orthodontic Bracket to Enamel Pretreated With Nd: YAG and Er: Cr, YSGG Lasers Using Curcumin-Hydroxyapatite Nanoparticles Infused Adhesive: A FTIR, SEM Evaluation via Backscattered Electron Imaging.

To evaluate the SBS, DC, and rheological valuation of experimental 1 wt % Cur-loaded-HNPs orthodontic adhesive to bond bracket to enamel surface treated with PA; Nd: YAG, and Er: Cr, YSGG lasers. Two adhesives were prepared experimental adhesive (EA) and EA loaded with 1-wt % Cur-HNP. Surface characterization of Cur-loaded HNP was performed under SEM along with EDS.

Correction: The relationship between political instability and stock market performance: An analysis of the MSCI index in the case of Pakistan.

[This corrects the article DOI: 10.1371/journal.pone.

New species and new records of the family Phytoseiidae Berlese (Acari: Mesostigmata) from Saudi Arabia.

A new species of the genus Neoseiulus Hughes (Acari: Mesostigmata: Phytoseiidae), belonging to the paspalivorus species group, N. arabicus sp. nov.

New species, new records and complementary descriptions of two species of the genus Tenuipalpus Donnadieu (Acari: Tenuipalpidae).

A new species of Tenuipalpus (Acari: Tenuipalpidae), Tenuipalpus farasanensis sp. nov., is described and illustrated based on female and male specimens collected from Salvadora spp.

Taxonomy of the Genus Koch (Acari: Tetranychidae): Reconsideration of Subgenera and Updated Species Groups.

The present study aimed to revise the subgeneric divisions of the genus based on persistent characteristics and to propose species groups in each subgenus to further ease the identification of species. As a result, only three subgenera, based on literature, are recognized, viz, subgenus Koch (duplex setae present on leg tarsi III-IV), subgenus Livschits and Mitrofanov (duplex setae absent on leg tarsi III-IV), and subgenus Livschits and Mitrofanov (duplex setae present only on leg tarsus III). The analysis based on morphological characters and available COI sequences on the GenBank database did not resolve the phylogenetic relationship of species, and likewise, no support could be found for the proposed subgeneric divisions.

Comparative efficiency of Geotrichum candidum microcapsules prepared with alginate and in combination with other polymers: In vitro evaluation.

Microencapsulation is utilized to protect probiotics, such as Geotrichum candidum, ensuring their survival, stability, and targeted release. The encapsulation efficiency depends on factors such as the type and concentration of the polymers and the encapsulation method. In this study, G.

Boron toxicity in plants: understanding mechanisms and developing coping strategies; a review.

Boron is essential for plants, but excess can induce toxicity. Boron (B) is a vital micronutrient for plants, but excess B can induce toxicity symptoms and reduce crop yields. B bioavailability depends on soil properties, including clay type, pH, and organic matter content.

Facile Synthesis of a Novel Furanic Monomer and Its ADMET Polymerization toward Fully Renewable Functional Polymers.

Efficient and sustainable transformation of biomass-derived chemicals to materials with the potential to replace conventional fossil-derived polymers is considered a major challenge. In this work, we disclose the synthesis of a novel furan-based α,ω-diene monomer following a facile, green, and energy-efficient process from fully renewable starting materials. The multifunctional monomer was produced by the base-catalyzed cross-aldol condensation of 10-undecenal (UA) and 2,5-diformylfuran (DFF) under mild conditions, providing the desired product in good yields.

Photoactivated riboflavin-doped hydroxy apatite nanospheres infiltered in orthodontic adhesives.

To assess micro-tensile bond strength (μTBS), degree of conversion (DC), microleakage (ML) antibacterial efficacy, and adhesive remnant index (ARI) of orthodontic brackets to enamel with different concentrations of photoactivated riboflavin-doped hydroxyapatite (HA) nanospheres (NS) (0%,1%,5% and 10%) and 0.5 wt% RF alone in orthodontic adhesive. Samples were included on the predefined inclusion criteria and positioned up to the cementoenamel junction (CEJ).

Species groups, subgroups, and key to world species of the genus Trägårdh, 1915 (Acari, Prostigmata, Tetranychidae).

After a comprehensive taxonomic assessment of descriptions/ illustrations of all known (118) species of the spider mite genus Trägårdh (Acari: Prostigmata: Tetranychidae), five species groups are proposed based on the number of tactile setae on tibia II in female, i.e., with four setae (four spp.

Complications and Revision Surgery in Orthopedics Focusing on Traumatology.

Background: Orthopedic traumatology, a vital component of orthopedic surgery, poses significant challenges in managing complications and necessitating revision surgeries. These challenges impact clinical outcomes, healthcare economics, and patient well-being.

Objective: This study aimed to provide insights that informed clinical decision-making and improved patient outcomes by thoroughly examining the range of complications encountered in orthopedic traumatology.

Phytochemical investigation of Chrysanthellum americanum Vatke and its constituents- a targeted approach for the treatment of leishmaniasis.

The present study is focused on the isolation and identification of new therapeutic candidates from Chrysanthellum americanum Vatke., and their efficacy against pteridine reductase-1 (PTR1), a valid chemotherapeutic target in the Leishmania parasite. Henceforth, a new compound, chrysanamerine (1), along with 7 known compounds, polyacetylene 2, and flavonoids 3-8, were isolated from C.

Artificial Intelligence and Machine Learning in Predicting Intradialytic Hypotension in Hemodialysis Patients: A Systematic Review.

Intradialytic hypotension (IDH) is a common and potentially life-threatening complication in hemodialysis patients. Traditional preventive measures have shown limited effectiveness in reducing IDH incidence. This systematic review evaluates the existing literature on the use of artificial intelligence (AI) and machine learning (ML) models for predicting IDH in hemodialysis patients.

Quantitative proteomics reveals significant variation in host responses of cattle with differing buffalo fly susceptibility.

Background: Control of buffalo flies (, BFs) relies mainly on chemical methods; however, resistance to insecticides is widespread in BF populations. Breeding for resistance to BFs represents a possible alternative, but direct phenotyping of animals is laborious and often inaccurate. The availability of reliable diagnostic biomarker(s) to identify low BF carrier cattle would facilitate rapid and accurate selection for genetic improvement.

Identification of QTLs associated with yield-related traits and superior genotype prediction using recombinant inbred line population in tobacco.

Tobacco is an economically significant industrial crop and model plant for genetic research, yet little is known about its genetic architecture. Quantitative trait loci (QTL) analysis was performed for six agronomic traits on an F_7 population of 341 genotypes, parents, and F plants using 1974 SSR markers across two environments. 31 QTLs contributing single-locus additive effects on 13 linkage groups (LGs) and 6 QTL pairs contributing epistatic effects on 6 LGs, were detected by the QTLNetwork 2.

Assessment of changes in enamel colour following fixed orthodontic therapy using an advanced spectrophotometer: An in vivo study.

Background: Any manipulation of the surface of natural teeth may result in a variation of their colour. The fixed orthodontic treatment (FOT) is one such procedure which alters the enamel surface during the procedure.

Objective: To clinically evaluate the colour changes in teeth associated with comprehensive FOT (to compare the changes in test and control groups) and to determine the relationship of age and gender on enamel colour due to FOT by using an advanced spectrophotometer.

Validation of SNPs for Milk Productivity of Sahiwal Breed (), Pakistan.

The aim of the present study was the validation of the already reported SNPs in the Sahiwal breed. A total of nine SNPs of the casein gene were studied. Out of nine, seven SNPs of casein protein genes were found to be significantly associated with milk productivity traits.