Publications by authors named "Muhammad Hassan"

Recent studies have suggested an evolving understanding of the association between vaping, specifically electronic cigarette (e-cigarette) use, and the progression of atherosclerosis, a significant contributor to cardiovascular disease. Despite the prevailing perception of vaping as a safer alternative to traditional tobacco smoking, accumulating evidence suggests that the aerosols emitted by e-cigarettes contain harmful constituents that may promote endothelial dysfunction, oxidative stress, inflammation, and dyslipidemia-key mechanisms implicated in atherosclerosis pathogenesis. While past research, including experimental studies and clinical investigations, has shed light on the potential cardiovascular risks associated with vaping, gaps in knowledge persist.

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Uncontrolled inflammation is the driver of numerous lung diseases. Current treatments, including corticosteroids and bronchodilators, can be effective. However, they often come with notable side effects.

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Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) can be isolated from umbilical cords which is abundant and easy to obtain. Due to their potent immunosuppressive properties, multilineage differentiation potential, and lack of ethical issues, WJ-MSCs are considered a promising candidate for therapeutic applications. However, large-scale in vitro expansion is necessary to obtain enough cells for therapeutic purposes.

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Biofilm-associated infections arising from antibiotic-resistant bacteria pose a critical challenge to global health. We report the generation of a library of cationic conjugated poly(phenylene ethynylene) (PPE) polymers featuring trimethylammonium terminated sidechains with tunable hydrophobicity. Screening of the library identified an amphiphilic polymer with a C hydrophobic spacer as the polymer with the highest antimicrobial efficacy against biofilms in the dark with excellent selectivity.

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Rice ( L.) feeds half the world's population and serves as one of the most vital staple food crops globally. The brown planthopper (BPH, Stål), a major piercing-sucking herbivore specific to rice, accounts for large yield losses annually in rice-growing areas.

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This study examines the effects of energy resources in the form of clean and unclean energy on the economic progress of 30 selected developed economies. This study used data from 1990 to 2020 and it employs the CS-ARDL method to obtain results. The results present that both clean and unclean energy significantly stimulate economic progress.

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Porphyrazine and tetrakis porphyrazine are examples of organic compounds with complicated structures of rings. Physicists and chemical researchers have been interested in these structures because of their highly conjugated systems, which lead to peculiar optical and electrical characteristics. These structures are the fundamental components of molecular electronics, sensors, functional materials, and catalysis, among other scientific fields.

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  • Liposarcoma of the uterine corpus is an extremely rare tumor with distinctive characteristics and treatment difficulties, as shown in a case study of a 57-year-old woman.
  • The patient initially had surgery and chemotherapy after presenting with severe abdominal issues, but faced multiple recurrences over the following years, including a more aggressive form of the tumor.
  • This case emphasizes the need for careful monitoring and individualized treatment plans to tackle the aggressive behavior of recurrent liposarcoma, particularly when it transforms into a dedifferentiated form.
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Current therapeutic strategies for benign prostatic hyperplasia (BPH) and prostate cancer focus mainly on androgen receptors (AR) and 5-alpha reductase inhibition to suppress androgen-driven prostate growth. However, these methods often result in side effects and resistance. Recent research identifies novel targets like integrin and cadherin inhibitors, gene regulation, microRNAs, cellular senescence, and metabolomics pathways to overcome these limitations.

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Satsumanus Ishihara is a small leafhopper genus in tribe Opsiini with six described species, and each have a very restricted biogeographical distribution in the Australian, Oriental and Palearctic regions. The species Satsumanus satsumae (Matsumura) is recorded for the first time from Zhejiang Province, and a new species Satsumanus discedens sp. nov.

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A catalog of the species and subspecies of Neuropterida (Insecta: Neuroptera, Megaloptera, and Raphidioptera) occurring in modern India is presented, based primarily on an extensive review of relevant literature published through mid 2024. The currently known extant fauna comprises 3 orders, 15 families, 129 genera, 368 species, and 6 subspecies (Neuroptera: 11 families, 119 genera, 332 species; Megaloptera: 2 families, 8 genera, 31 species; Raphidioptera: 2 families, 2 genera, 5 species). In addition, one extinct species is known, †Spiloconis eominuta (Neuroptera: Coniopterygidae).

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Background: The genus is reviewed with seven species found in Pakistan: (Mulsant, 1866), Kapur, 1973, Dobzhansky, 1926, Fabricius, 1781, Linnaeus, 1758, Faldermann, 1835 and Linnaeus, 1758. Information on prey, host plants, distribution and an identification key for species in Pakistan is provided. Additionally, newly-sequenced partial COI (cytochrome-c-oxidase subunit I) for and were used to determine their phylogenetic positions within the genus .

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  • Premature ventricular beats during pregnancy can lead to serious complications like palpitations, reduced placental blood flow, and risks for the fetus, including miscarriage.
  • A case study highlights the successful use of radiofrequency catheter ablation on a pregnant woman with a rare focus of these beats, demonstrating both the challenges and positive outcomes of the procedure.
  • The use of fluoroscopy-less ablation is beneficial as it minimizes radiation exposure while ensuring a high success rate and safety for pregnant patients.
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Antimony (Sb) toxicity is a significant threat to crop production and humans. Its concentration is increasing in soil and water due to human activities which needs dire attention to address this challenge. Biochar is a promising amendment to remediate polluted soils, however, its role in mitigating the toxic impacts of Sb on plants is still unclear.

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Introduction: Silent myocardial ischemia (SMI) is a significant concern for diabetic patients, often remaining undetected until severe complications arise. Prolonged hyperglycemia, poor glycemic control, and lifestyle factors contribute to its risk, with older adults and those with long-standing diabetes particularly vulnerable.

Objective: To assess the prevalence and predictors of SMI in adults with diabetes, emphasizing long-term management and monitoring.

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Background: Previously, most researchers explored the association between chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD). This study investigates the distinct influence of COVID-19 vaccination status on patients with both conditions.

Objective: We investigate the relationship between COPD and CVD in a cohort of 838 individuals who presented with both conditions.

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  • - Cerebral palsy (CP) is a neurological disorder resulting from issues during fetal brain development, emphasizing the need for early intervention and monitoring of brain development in affected children.
  • - This study explores the relationship between biological traits (BTs) and neurodevelopmental differences in healthy children (HC) versus those with CP, aiming to set a benchmark for these associations.
  • - Using a specialized neural network (AWG-Net) for analysis, findings indicate that age, gender, and weight significantly impact brain regions in both HC and CP children, with age and weight being particularly influential in understanding CP-related vulnerabilities.
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Antimony (Sb) toxicity is a serious concern due to its harmful effects on humans and plants. Biochar (BC) has become a popular amendment for remediating soils polluted with metals and metalloids. However, the exact interaction mechanism between BC, and microbes to remediate Sb-polluted soils remains unclear.

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  • Sepsis is a life-threatening condition with high rates of illness and mortality, requiring early detection and evaluation of its severity for effective treatment.
  • A study conducted on 201 ICU patients in Pakistan aimed to assess the relationship between serum albumin levels and sepsis severity using the SOFA scoring system.
  • Results showed that many patients had low albumin levels (hypoalbuminemia), indicating potential that serum albumin could be a useful predictor for assessing the severity of sepsis.
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Ferroptosis, a regulated form of cell death driven by oxidative stress and lipid peroxidation, has emerged as a pivotal research focus with implications across various cellular contexts. In this study, we employed a multifaceted approach, integrating label-free Raman spectroscopy and microfluidics to study the mechanisms underpinning ferroptosis. Our investigations included the ferroptosis initiation based on the changes in the lipid Raman band at 1436 cm under different cellular states, the generation of reactive oxygen species (ROS), lipid peroxidation, DNA damage/repair, and mitochondrial dysfunction.

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An efficacious strategy to adapt to climate change involves optimizing the planting season, a technique that has been extensively utilized to enhance the use of solar radiation and temperature resources in rice cultivation. Field experiments were executed in the middle and lower reaches of the Yangtze River, China, employing three distinct rice cultivars and seven disparate sowing periods spanning 2019 to 2021. The objective of assessing the impact of sowing date on apparent radiation use efficiency (RUE), accumulated temperature use efficiencies (TUE), and overall rice yield.

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Diethyl aminoethyl hexanoate (DA-6) serving as a non-toxic and low-cost plant growth regulator is used for improving plant growth and stress tolerance, but the DA-6-mediated organic metabolites remodeling in relation to drought tolerance is not well documented in crops. The aims of the present study were to evaluate impacts of DA-6 on physiological functions including osmotic adjustment, photochemical efficiency, oxidative damage, and cell membrane stability as well as organic metabolites remodeling in white clover () leaves based on the analysis of metabolomics. Plants were foliarly treated with or without DA-6 and subsequently exposed to drought stress for 8 days.

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To achieve the rapid grade classification of camellia seed oil, hyperspectral imaging technology was used to acquire hyperspectral images of three distinct grades of camellia seed oil. The spectral and image information collected by the hyperspectral imaging technology was preprocessed by different methods. The characteristic wavelength selection in this study included the continuous projections algorithm (SPA) and competitive adaptive reweighted sampling (CARS), and the gray-level co-occurrence matrix (GLCM) algorithm was used to extract the texture features of camellia seed oil at the characteristic wavelength.

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