Strategic analysis of wind energy potential and optimal turbine selection in Al-Jouf, Saudi Arabia.

Wind power is considered one of the most environmentally friendly and rapidly growing form of renewable energy. This study aims at assessment of wind power potential for Al-Jouf region in Saudi Arabia. A long term historical wind speed data of 21 years (2000-2021) was analytically modeled using Weibull distribution function to determine the wind characteristics.

Sustainability assessment of machining Al 6061-T6 using Taguchi-grey relation integrated approach.

Modern machining requires reduction in energy usage, surface roughness, and burr width to produce finished or near-finished parts. To ensure high surface quality in machining processes, it is crucial to minimize surface finish and minimize burr width, which are considered as significant parameters as specific cutting energy. The objective of this study was to identify the optimal machining parameters for milling in order to minimize surface roughness, burr width, and specific cutting energy.

Non-Coding RNA-Mediated Gene Regulation in Cardiovascular Disorders: Current Insights and Future Directions.

Cardiovascular diseases (CVDs) pose a significant burden on global health. Developing effective diagnostic, therapeutic, and prognostic indicators for CVDs is critical. This narrative review explores the role of select non-coding RNAs (ncRNAs) and provides an in-depth exploration of the roles of miRNAs, lncRNAs, and circRNAs in different aspects of CVDs, offering insights into their mechanisms and potential clinical implications.

Investigation of Dielectric, Mechanical, and Thermal Properties of Epoxy Composites Embedded with Quartz Fibers.

Polymer matrix wave transparent composites are used in a variety of high-speed communication applications. One of the applications of these involves making protective enclosures for antennas of microwave towers, air vehicles, weather radars, and underwater communication devices. Material performance, structural, thermal, and mechanical degradation are matters of concern as advanced wireless communication needs robust materials for radomes that can withstand mechanical and thermal stresses.

Corrigendum: The prospective outcome of the Monkeypox outbreak in 2022 and characterization of monkeypox disease immunobiology.

[This corrects the article DOI: 10.3389/fcimb.2023.

Addressing sexual assault in Pakistan: Insights from an analysis of female survivors at Lahore General Hospital.

Background & Objective: Rape is a severe kind of sexual violence that represents a significant violation of human rights. The objective was to investigate the demographic and clinical features of female survivors of sexual assault in Lahore, Pakistan.

Method: A retrospective study was conducted at the Department of Forensic Medicine of Lahore General Hospital, analysing records of female sexual assault survivors investigated by affiliated police stations from November 2020 to November 2022.

Comparative Roles of IL-1, IL-6, IL-10, IL-17, IL-18, 1L-22, IL-33, and IL-37 in Various Cardiovascular Diseases With Potential Insights for Targeted Immunotherapy.

In recent years, the study of interleukins (ILs), crucial cytokines involved in immune response and inflammation, has garnered significant attention within the sphere of cardiovascular diseases (CVDs). The research has provided insights into the involvement of ILs in diverse CVDs, including arrhythmias, myocardial infarction, atherosclerosis, and heart failure (HF). ILs have emerged as promising therapeutic targets for drug interventions through their involvement in disease development and progression.

Unlocking the Mysteries, Bridging the Gap, and Unveiling the Multifaceted Potential of Stem Cell Therapy for Cardiac Tissue Regeneration: A Narrative Review of Current Literature, Ethical Challenges, and Future Perspectives.

Revolutionary advancements in regenerative medicine have brought stem cell therapy to the forefront, offering promising prospects for the regeneration of ischemic cardiac tissue. Yet, its full efficacy, safety, and role in treating ischemic heart disease (IHD) remain limited. This literature review explores the intricate mechanisms underlying stem cell therapy.

Advancements in Percutaneous Coronary Intervention Techniques: A Comprehensive Literature Review of Mixed Studies and Practice Guidelines.

Percutaneous coronary intervention (PCI) is a widely used therapy for coronary artery disease (CAD), but it carries risks and complications. Adhering to evidence-based practice guidelines is crucial for optimal outcomes. This review compares the recommendations of the 2021 American College of Cardiology/American Heart Association/Society for Cardiovascular Angiography and Interventions (ACC/AHA/SCAI) and 2018 European Society of Cardiology (ESC) guidelines for coronary artery revascularization and discusses emerging trends and novel devices in PCI.

The prospective outcome of the monkeypox outbreak in 2022 and characterization of monkeypox disease immunobiology.

A new threat to global health re-emerged with monkeypox's advent in early 2022. As of November 10, 2022, nearly 80,000 confirmed cases had been reported worldwide, with most of them coming from places where the disease is not common. There were 53 fatalities, with 40 occurring in areas that had never before recorded monkeypox and the remaining 13 appearing in the regions that had previously reported the disease.

Lack of knowledge regarding the misuse of domperidone in Pakistan and its serious consequences: short communication.

Domperidone is an antagonist of the peripheral dopamine (D2) receptor. It works as an antiemetic by blocking D2-receptors at the chemoreceptor trigger zone and as a gastroprokinetic drug by blocking GI tract D2-receptors. According to research, using domperidone significantly raises the risk of cardiac arrhythmia and sudden cardiac death by 70%, most likely through prolonging the QT interval.

The role of gut microbiota in depression: an analysis of the gut-brain axis.

The gut-brain axis is a communication pathway that allows a two-way exchange of information between the microbiota of the gastrointestinal tract and the nervous system of humans. The vagus nerve, which is responsible for facilitating communication, provides support for this axis. The gut-brain axis is currently the subject of research, but studies into the diversity and stratification of the gut microbiota are just getting started.

Autoimmune hemolytic anemia, a rare disease in newborns: a case report.

Unlabelled: Autoimmune hemolytic anemia (AIHA) is a type of hemolytic anemia in which autoantibodies attack the membrane antigens of red blood cells, causing cell rupture (lysis). Hemolysis stimulates compensatory RBC production by boosting erythropoietin levels; however, this response is often insufficient to restore normal hemoglobin blood levels, resulting in anemia. It is a rare disease, with an annual incidence of one case in every 80 000 live births.

Efficacy, Safety, and Role of Antiplatelet Drugs in the Management of Acute Coronary Syndrome: A Comprehensive Review of Literature.

Acute coronary syndrome (ACS) is a complex condition characterized by myocardial ischemia or infarction which can lead to significant morbidity and death. Antiplatelet drugs play a crucial role in the management of ACS and have been shown to minimize the incidence of significant adverse cardiovascular events and recurrent myocardial infarction (MI). This comprehensive literature review is intended to summarize current information on the effectiveness, safety, and function of frequently used antiplatelet medications in treating ACS.

Mechanical and Durability Evaluation of Metakaolin as Cement Replacement Material in Concrete.

Due to the increasing prices of cement and its harmful effect on the environment, the use of cement has become highly unsustainable in concrete. There is a considerable need for promoting the use of cement replacement materials. This study investigates the effect of variable percentages of metakaolin (MK) on the mechanical and durability performance of concrete.

Evaluating the Strength and Impact of Raw Ingredients of Cement Mortar Incorporating Waste Glass Powder Using Machine Learning and SHapley Additive ExPlanations (SHAP) Methods.

This research employed machine learning (ML) and SHapley Additive ExPlanations (SHAP) methods to assess the strength and impact of raw ingredients of cement mortar (CM) incorporated with waste glass powder (WGP). The data required for this study were generated using an experimental approach. Two ML methods were employed, i.

Investigating the Bond Strength of FRP Rebars in Concrete under High Temperature Using Gene-Expression Programming Model.

In recent times, the use of fibre-reinforced plastic (FRP) has increased in reinforcing concrete structures. The bond strength of FRP rebars is one of the most significant parameters for characterising the overall efficacy of the concrete structures reinforced with FRP. However, in cases of elevated temperature, the bond of FRP-reinforced concrete can deteriorate depending on a number of factors, including the type of FRP bars used, its diameter, surface form, anchorage length, concrete strength, and cover thickness.

Computational AI Models for Investigating the Radiation Shielding Potential of High-Density Concrete.

Concrete is an economical and efficient material for attenuating radiation. The potential of concrete in attenuating radiation is attributed to its density, which in turn depends on the mix design of concrete. This paper presents the findings of a study conducted to evaluate the radiation attenuation with varying water-cement ratio (/), thickness, density, and compressive strength of concrete.

Prediction Models for Evaluating Resilient Modulus of Stabilized Aggregate Bases in Wet and Dry Alternating Environments: ANN and GEP Approaches.

Stabilized aggregate bases are vital for the long-term service life of pavements. Their stiffness is comparatively higher; therefore, the inclusion of stabilized materials in the construction of bases prevents the cracking of the asphalt layer. The effect of wet−dry cycles (WDCs) on the resilient modulus (Mr) of subgrade materials stabilized with CaO and cementitious materials, modelled using artificial neural network (ANN) and gene expression programming (GEP) has been studied here.

Prediction of Strength and CBR Characteristics of Chemically Stabilized Coal Gangue: ANN and Random Forest Tree Approach.

Coal mining waste in the form of coal gangue (CG) was established recently as a potential fill material in earthworks. To ascertain this potential, this study forecasts the strength and California Bearing Ratio (CBR) characteristics of chemically stabilized CG by deploying two widely used artificial intelligence approaches, i.e.

Split Tensile Strength Prediction of Recycled Aggregate-Based Sustainable Concrete Using Artificial Intelligence Methods.

Sustainable concrete is gaining in popularity as a result of research into waste materials, such as recycled aggregate (RA). This strategy not only protects the environment, but also meets the demand for concrete materials. Using advanced artificial intelligence (AI) approaches, this study anticipates the split tensile strength (STS) of concrete samples incorporating RA.

A Network Intrusion Detection System Using Hybrid Multilayer Deep Learning Model.

An intrusion detection system (IDS) is designed to detect and analyze network traffic for suspicious activity. Several methods have been introduced in the literature for IDSs; however, due to a large amount of data, these models have failed to achieve high accuracy. A statistical approach is proposed in this research due to the unsatisfactory results of traditional intrusion detection methods.

Multi Expression Programming Model for Strength Prediction of Fly-Ash-Treated Alkali-Contaminated Soils.

Rapid industrialization is leading to the pollution of underground natural soil by alkali concentration which may cause problems for the existing expansive soil in the form of producing expanding lattices. This research investigates the effect of stabilizing alkali-contaminated soil by using fly ash. The influence of alkali concentration (2 N and 4 N) and curing period (up to 28 days) on the unconfined compressive strength (UCS) of fly ash (FA)-treated (10%, 15%, and 20%) alkali-contaminated kaolin and black cotton (BC) soils was investigated.

Forecasting Compressive Strength of RHA Based Concrete Using Multi-Expression Programming.

Rice husk ash (RHA) is a significant pollutant produced by agricultural sectors that cause a malignant outcome to the environment. To encourage the re-use of RHA, this work used multi expression programming (MEP) to construct an empirical model for forecasting the compressive nature of concrete made with RHA (CRHA) as a cement substitute. Thus, the compressive strength of CRHA was developed comprising of 192 findings from the broad and trustworthy database obtained from literature review.