Comparative bioavailability study of supplemental oral Sucrosomial vs. oral conventional vitamin B12 in enhancing circulatory B12 levels in healthy deficient adults: a multicentre, double-blind randomized clinical trial.

Background: Vitamin B12 is essential for neurological function, red blood cell formation, and DNA synthesis. Deficiency can lead to diverse health conditions, including megaloblastic anemia and neurological issues. Oral supplementation is a standard treatment for B12 deficiency.

Interstitial Lung Abnormality: Narrative Review of the Approach to Diagnosis and Management.

Topic Importance: As interstitial lung abnormalities (ILAs) are increasingly recognized on imaging and in clinical practice, identification and appropriate management are critical. We propose an algorithmic approach to the identification and management of patients with ILAs.

Review Findings: The radiologist initially identifies chest CT scan findings suggestive of an ILA pattern and excludes findings that are not consistent with ILAs.

Retraction notice to "Seasonal correlation of aerosols with soil moisture, evapotranspiration, and vegetation over Pakistan using remote sensing" [Heliyon (2023) e20635].

[This retracts the article DOI: 10.1016/j.heliyon.

Characterization of Near Infrared-Dye Colored Fabrics Using Hyperspectral Imaging.

Near-infrared (NIR) dyes have a unique ability to interact favorably with light in the NIR region, which is particularly interesting where stealth and camouflage are paramount, such as in military uniforms. Characterization of cotton fabric dyed with NIR-absorbing dyes using visible-NIR (Vis-NIR) and short-wave infrared (SWIR) hyperspectral imaging was done. The aim of the study was to discern spectral changes caused by variations in dye concentration and dyeing temperature as these parameters directly influence color- and crocking-fastness of fabrics impacting the camouflage effect.

The mediating role of stakeholders on green banking practices and bank's performance: The case of a developing nation.

The banking sector serves as a nudge between increased financial investments and reduced environmental impacts in the modern era of sustainability thus, integrating the social, environmental, and economic dimensions. This paper aims to explore the practices and ongoing activities on account of sustainable banking which is being practised in the Pakistani Banking Sector. A mixed methods approach using a survey with a sample size of (n = 250) and in-depth interviews of (n = 25) provides significant evidence for the research.

Surface slicing and toolpath planning forbioprinting of skin implants.

Bioprinting has emerged as a successful method for fabricating engineered tissue implants, offering great potential for wound healing applications. This study focuses on an advanced surface-based slicing approach aimed at designing a skin implant specifically forbioprinting. The slicing step plays a crucial role in determining the layering arrangement of the tissue during printing.

pNaKtide Inhibits Na/K-ATPase Signaling and Attenuates Obesity.

Obesity is a growing public health crisis across the world and has been recognized as an underlying risk factor for metabolic syndrome. Growing evidence demonstrates the critical role of oxidative stress in the pathophysiological mechanisms of obesity and related metabolic dysfunction. As we have established previously that Na/K-ATPase can amplify oxidative stress signaling, we aimed to explore the effect of inhibition of this pathway on obesity phenotype using the peptide antagonist, pNaKtide.

Quality Characterization of Fava Bean-Fortified Bread Using Hyperspectral Imaging.

As the demand for alternative protein sources and nutritional improvement in baked goods grows, integrating legume-based ingredients, such as fava beans, into wheat flour presents an innovative alternative. This study investigates the potential of hyperspectral imaging (HSI) to predict the protein content (short-wave infrared (SWIR) range)) of fava bean-fortified bread and classify them based on their color characteristics (visible-near-infrared (Vis-NIR) range). Different multivariate analysis tools, such as principal component analysis (PCA), partial least square discriminant analysis (PLS-DA), and partial least square regression (PLSR), were utilized to assess the protein distribution and color quality parameters of bread samples.

Assessment of Mechanical Damage and Germinability in Flaxseeds Using Hyperspectral Imaging.

The high demand for flax as a nutritious edible oil source combined with increasingly restrictive import regulations for oilseeds mandates the exploration of novel quantity and quality assessment methods. One pervasive issue that compromises the viability of flaxseeds is the mechanical damage to the seeds during harvest and post-harvest handling. Currently, mechanical damage in flax is assessed via visual inspection, a time-consuming, subjective, and insufficiently precise process.

Investigation of vibration's effect on driver in optimal motion cueing algorithm.

The increased sensation error between the surroundings and the driver is a major problem in driving simulators, resulting in unrealistic motion cues. Intelligent control schemes have to be developed to provide realistic motion cues to the driver. The driver's body model incorporates the effects of vibrations on the driver's health, comfort, perception, and motion sickness, and most of the current research on motion cueing has not considered these factors.

Evaluating the effect of environmental conditions on high compressive strain rates in unfilled and filled neoprene rubbers.

Elastomers are known for their strain-rate-dependent properties not only to quasistatic but also to high strain rate deformations, where mechanical behavior is significantly affected by inertia. Concurrently, environmental changes, such as temperature and humidity variations, can impact their stress response to deformation. This study investigates the effects of material layers within neoprene samples on mitigating these environmental changes.

Characterization and applications of glutaminase free L-asparaginase from indigenous Bacillus halotolerans ASN9.

L-asparaginase (L-ASNase) is a versatile anticancer and acrylamide reduction enzyme predominantly used in medical and food industries. However, the high specificity of L-asparaginase formulations for glutamine, low thermostability, and blood clearance are the major disadvantages. Present study describes production, characterization, and applications of glutaminase free extracellular L-asparaginase from indigenous Bacillus halotolerans ASN9 isolated from soil sample.

Seasonal correlation of aerosols with soil moisture, evapotranspiration, and vegetation over Pakistan using remote sensing.

Aerosols have a severe impact on the Earth's climate, human health, and ecosystem. To understand the impacts of aerosols on climate, human health, and the ecosystem we must need to understand the variability of aerosols and their optical properties. Therefore, we used Aqua-MODIS retrieved aerosol optical depth (AOD) (550 nm) and Angstrom exponent (AE) (440/870) data to analyze the Spatio-temporal seasonal variability of aerosols and their relationship with different meteorological parameters over Pakistan from 2002 to 2021.

Formal modeling and analysis of security schemes of RPL protocol using colored Petri nets.

In the Internet of things (IoT), data packets are accumulated and disseminated across IoT devices without human intervention, therefore the privacy and security of sensitive data during transmission are crucial. For this purpose, multiple routing techniques exist to ensure security and privacy in IoT Systems. One such technique is the routing protocol for low power and lossy networks (RPL) which is an IPv6 protocol commonly used for routing in IoT systems.

Characterization of Mode I and Mode II Interlaminar Fracture Toughness in CNT-Enhanced CFRP under Various Temperature and Loading Rates.

This study investigates the influence of temperature and loading rate on the Mode I and Mode II interlaminar fracture behavior of carbon-nanotubes-enhanced carbon-fiber-reinforced polymer (CNT-CFRP). CNT-induced toughening of the epoxy matrix is characterized by producing CFRP with varying loading of CNT areal density. CNT-CFRP samples were subjected to varying loading rates and testing temperatures.

Inhibition of Na/K-ATPase signaling Attenuates Steatohepatitis and Atherosclerosis in Mice Fed a Western Diet.

We have previously reported that the α1 subunit of sodium-potassium adenosine triphosphatase (Na/K-ATPase), acts as a receptor and an amplifier for reactive oxygen species, in addition to its distinct pumping function. On this background, we speculated that the blockade of Na/K-ATPase-induced ROS amplification with a specific peptide, pNaKtide, might attenuate the development of steatohepatitis. To test this hypothesis, pNaKtide was administered to a murine model of NASH: the C57Bl6 mouse fed a "western" diet containing high amounts of fat and fructose.

Early Identification of Crop Type for Smallholder Farming Systems Using Deep Learning on Time-Series Sentinel-2 Imagery.

Climate change and the COVID-19 pandemic have disrupted the food supply chain across the globe and adversely affected food security. Early estimation of staple crops can assist relevant government agencies to take timely actions for ensuring food security. Reliable crop type maps can play an essential role in monitoring crops, estimating yields, and maintaining smooth food supplies.

Quercetin as a possible complementary agent for early-stage COVID-19: Concluding results of a randomized clinical trial.

Quercetin, a natural polyphenol with demonstrated broad-spectrum antiviral, anti-inflammatory, and antioxidant properties, has been proposed as an adjuvant for early-stage coronavirus disease 2019 (COVID-19) infection. To explore the possible therapeutic effect of quercetin in outpatients with early-stage mild to moderate symptoms of COVID-19. This was an open-label randomized controlled clinical trial conducted at the department of medicine, King Edward Medical University, Lahore, PK.

Vitamin D Deficiency (VDD) and Susceptibility towards Severe Dengue Fever-A Prospective Cross-Sectional Study of Hospitalized Dengue Fever Patients from Lahore, Pakistan.

Dengue is a mosquito-borne flaviviral serious febrile illness, most common in the tropical and subtropical regions including Pakistan. Vitamin D is a strong immunomodulator affecting both the innate and adaptive immune responses and plays a pivotal role in pathogen-defense mechanisms. There has been considerable interest in the possible role of vitamin D in dengue viral (DENV) infection.

Global ecological niche conservatism and evolution in species.

Background And Aims: Climate is an important parameter in delimiting coarse-grained aspects of fundamental ecological niches of species; evolution of these niches has been considered a key component in biological diversification. We assessed phylogenetic niche conservatism and evolution in 24 species of the family Oleaceae in relation to temperature and precipitation variables. We studied niches of 17 species and 7 species from other genera of Oleaceae globally.

High-Strain-Rate Compression of Elastomers Subjected to Temperature and Humidity Conditions.

Elastomers exhibit a complex response to high-strain-rate deformation due to their viscoelastic behaviour. Environmental conditions highly impact this behaviour, especially when both temperature and humidity change. In several applications where elastomers are used, the quantity of real humidity might vary, especially when the temperature is elevated.

Spatial distribution and computational modeling for mapping of tuberculosis in Pakistan.

Background: Tuberculosis (TB) like many other infectious diseases has a strong relationship with climatic parameters.

Methods: The present study has been carried out on the newly diagnosed sputum smear-positive pulmonary TB cases reported to National TB Control Program across Pakistan from 2007 to 2020. In this study, spatial and temporal distribution of the disease was observed through detailed district wise mapping and clustered regions were also identified.