Publications by authors named "Muhammad Adeel Hasnain"
Food Sci Biotechnol
July 2024
Article Synopsis
- The gut microbiota, mostly made up of bacteria, is essential for the host's health by aiding in energy metabolism, disease protection, and immune function.
- Dysbiosis, which refers to an imbalance in the gut microbiota, can lead to various health issues, including gastrointestinal and neurological disorders.
- Next-generation probiotics are being developed using advanced technologies to target specific imbalances and disorders, with ongoing research focusing on how to effectively implement these tailored solutions in health care.
Article Synopsis
- The bacteriophage CAP 10-3, isolated from human skin acne lesions, has a genome consisting of 29,643 bp with a GC content of 53.86%, showing a high similarity to another phage, PAP 1-1.
- Bioinformatic analysis revealed 147 open reading frames (ORFs) and identified functions for 40 of those, including a significant endolysin gene associated with antibacterial activity against Cutibacterium acnes.
- The recombinant endolysin was successfully expressed in E. coli and demonstrated effective antibacterial properties, indicating its potential as a therapeutic agent for treating acne.
