Publications by authors named "Muhammad A Alfawaz"
Nat Prod Commun
February 2013
Article Synopsis
- Nigella sativa (black cumin) has demonstrated significant potential in inhibiting the growth of human cervical cancer cells, specifically SiHa, with a notable 88.3% reduction in cell proliferation observed at a concentration of 125 µL/mL.
- The study found that Nigella sativa extract activates key proteins involved in apoptosis, specifically increasing the expression of caspases-3, -8, and -9.
- Overall, the research suggests that Nigella sativa could serve as a promising alternative treatment option for cervical cancer by promoting cell death through a mechanism involving p53 and caspase activation.
