The state of renal sympathetic denervation for the management of patients with hypertension: A systematic review and meta-analysis.

Background: Sympathetic nervous system plays a central role in the development and persistence of essential hypertension. In recent years renal sympathetic denervation (RSD) has emerged as a promising option for the treatment of patients with hypertension.

Methods: We conducted a literature search of PubMed, EMBASE, Cochrane library and Clinicaltrials.

Isolated Pulmonic Valve Endocarditis: Case Report and Review of Existing Literature on Diagnosis and Therapy.

• Pulmonic valve endocarditis (PVE) is a rare complication of infective endocarditis. • It is occasionally associated with significant pulmonic insufficiency (PI). • PVE usually has a benign course, but it can sometimes be complicated.

Trial Sequential Analysis Comparing Bleeding and Major Adverse Cardiovascular Events in Patients with Atrial Fibrillation and Acute Coronary Syndrome on Dual versus Triple Therapy.

Objective To assess efficacy and safety of dual therapy (DT) and triple therapy (TT) in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS) with or without percutaneous coronary intervention (PCI) and evaluate the quality of evidence with respect to said outcomes based on contemporary randomized trials (RCTs). The efficacy outcome taken was major adverse cardiovascular events (MACE) while safety outcome was major bleeding events. Introduction Appropriate anti-thrombotic therapy is still controversial in patients with AF and concomitant ACS or PCI.

Story of an Unfortunate Fall: Cardiac Contusion Presenting with an Atrioventricular Block.

Blunt cardiac injury (BCI), also referred to in the literature as a cardiac contusion, is a known cause of myocardial injury. It is often challenging to diagnose this condition in the absence of clear diagnostic criteria. Furthermore, its clinical presentation is highly variable depending on the severity, type, and duration of the trauma, as well as the timing from the initial insult.