Piper sarmentosum Effects on 11β-Hydroxysteroid Dehydrogenase Type 1 Enzyme in Serum and Bone in Rat Model of Glucocorticoid-Induced Osteoporosis.

Glucocorticoid-induced osteoporosis is one of the common causes of secondary osteoporosis. () extract possesses antioxidant and anti-inflammatory activities. In this study, we determined the correlation between the effects of leaf water extract with the regulation of 11β-hydroxysteroid dehydrogenase (HSD) type 1 enzyme activity in serum and bone of glucocorticoid-induced osteoporotic rats.