Publications by authors named "Muhaddisa Barat Ali"

Background: Deep learning (DL) has shown promising results in molecular-based classification of glioma subtypes from MR images. DL requires a large number of training data for achieving good generalization performance. Since brain tumor datasets are usually small in size, combination of such datasets from different hospitals are needed.

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In most deep learning-based brain tumor segmentation methods, training the deep network requires annotated tumor areas. However, accurate tumor annotation puts high demands on medical personnel. The aim of this study is to train a deep network for segmentation by using ellipse box areas surrounding the tumors.

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Article Synopsis
  • The study explores the use of tumor bounding box areas from MRIs for classifying brain tumor subtypes instead of relying on time-consuming manual annotations by experts.
  • By training a deep learning classifier with these bounding box areas from patients with diffuse gliomas, they tested the method on two datasets and achieved satisfactory prediction rates.
  • The results indicate that using bounding boxes leads to only a small decrease in prediction accuracy compared to using annotated ground truth data, suggesting a viable alternative for tumor classification.
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The use of deep learning (DL) is rapidly increasing in clinical neuroscience. The term denotes models with multiple sequential layers of learning algorithms, architecturally similar to neural networks of the brain. We provide examples of DL in analyzing MRI data and discuss potential applications and methodological caveats.

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Brain tumors, such as low grade gliomas (LGG), are molecularly classified which require the surgical collection of tissue samples. The pre-surgical or non-operative identification of LGG molecular type could improve patient counseling and treatment decisions. However, radiographic approaches to LGG molecular classification are currently lacking, as clinicians are unable to reliably predict LGG molecular type using magnetic resonance imaging (MRI) studies.

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