Distribution of maternal risk factors for orofacial cleft in infants in Indonesia: a multicenter prospective study.

Background: The pathogenesis of orofacial cleft (OFC) is multifactorial, involving both genetic and non-genetic factors, the latter of which play a key role in the development of these anomalies. This paper addresses the incidence of OFC in Indonesia, with a focus on identifying and examining the distribution of contributory factors, including parental medical history, pregnancy history, and environmental influences.

Methods: The study was conducted through the collection of primary data.