Publications by authors named "Muge Ildizli"
Background And Aims: Familial hypercholesterolemia (FH) is a common genetic disease of high-level cholesterol leading to premature atherosclerosis. One of the key aspects to overcome FH burden is the generation of large-scale reliable data in terms of registries. This manuscript underlines the important results of nation-wide Turkish FH registries (A-HIT1 and A-HIT2).
View Article and Find Full Text PDFBackground: Statins may provide additional benefits in patients with cardiac failure due to their pleiotropic effects besides their cholesterol-lowering actions. In this study, we aimed to evaluate the impact of 12-week fluvastatin therapy on the inflammatory cytokines and the ventricular performance markers in patients with heart failure.
Methods And Results: Fourty chronic heart failure patients, twenty with idiopathic dilated cardiomyopathy (DCM group) and 20 with ischemic cardiomyopathy (ICM group), for whom statin treatment was indicated according to Adult Treatment Panel III were included to this open label and prospective study.
Article Synopsis
- The study investigates the impact of long-term regular exercise on myocardial function, comparing professional football players with age-adjusted sedentary controls.
- Both groups were similar in age, body surface area, blood pressure, and heart rate; however, the athletes showed significant increases in left ventricular mass, volume, and diastolic function measurements.
- Overall, the findings suggest that regular athletic training leads to beneficial cardiac adaptations, including enhanced early diastolic velocities and improved early flow propagation velocity in professional athletes.
Although factor V Leiden mutation, is the most common established genetic risk factor for venous thrombosis, its effect on the development of myocardial infarction remains unclear. We describe a family case of homozygous factor V Leiden mutation in two siblings presenting with acute myocardial infarction as a rare cause of myocardial infarction in the young.
View Article and Find Full Text PDFIsotretinoin (13-cis-retinoic acid) associated atrial tachycardia.
Pacing Clin Electrophysiol
April 2005
Article Synopsis
- A 16-year-old boy experienced palpitations for a week while taking isotretinoin for acne, after three months of treatment.
- Holter monitoring revealed he had frequent premature atrial beats and non-sustained atrial tachycardia, which he had never experienced before.
- His symptoms nearly disappeared within a week after stopping the medication, indicating that isotretinoin may have caused the heart issues, suggesting that doctors should be cautious about its potential arrhythmogenic effects.