Nutritional Status Is Associated with Mortality but Not Appropriate Discharge of Implantable Cardioverter Defibrillators in Patients with Heart Failure.

To investigate the predictive value of nutritional status in heart failure (HF) patients with an implantable cardioverter defibrillator (ICD), and to identify factors associated with ICD discharge and mortality. This retrospective study was conducted by analyzing data from 2017 to 2021. HF patients who underwent ICD implantation for primary prevention were included.

Detection of Gallbladder Disease Types Using a Feature Engineering-Based Developed CBIR System.

Early detection and diagnosis are important when treating gallbladder (GB) diseases. Poorer clinical outcomes and increased patient symptoms may result from any error or delay in diagnosis. Many signs and symptoms, especially those related to GB diseases with similar symptoms, may be unclear.

Comparing Behavioral and Neural Activity Changes During Laparoscopic and Robotic Surgery Trainings.

Objective: This study aims to compare the cognitive workload levels of general surgery residents by measuring prefrontal cortex hemodynamic activity while performing a similar task using robotic-assisted surgery (RAS) and laparoscopic surgery simulators.

Design: The study was conducted with 22 general surgery residents who completed a peg transfer task in simulated laparoscopic and RAS training environments. Participants' performance and neurophysiological data were collected over a 1-month period.

Evaluation of Accommodation Amplitude and Convergence Insufficiency in Patients with Multiple Sclerosis.

Purpose: To evaluate the near reflex components, including accommodation, convergence, and binocular fusional vergences in patients with multiple sclerosis (MS).

Material-method: MS patients under 35 years of age without visual evoked potential (VEP) abnormalities (MS Group) and age-matched healthy individuals of (Control Group) were included in the study. Fusional vergence amplitudes, the amplitude of accommodation (AA), stereopsis measurements, near-object fixation and near point of convergence (NPC) measurements, Convergence Insufficiency Symptoms Survey (CISS) results, and the presence of nystagmus were recorded retrospectively from the files of the cases.

Genotoxic and cytotoxic effects of polystyrene nanoplastics on human lymphocytes: A comprehensive analysis.

A growing amount of plastic waste is finding its way into natural ecosystems as a result of the widespread usage of plastics in modern society. These wastes degrade physically and biologically over time, transforming into microplastics (MPs) and nanoplastics (NPs). MPs and NPs emissions from the terrestrial environment then mix with rivers and eventually the seas, forming garbage.

The Psychometric Properties of the Turkish Version of the Stress Scale for Siblings of Childhood Cancer Patients.

Aim: This study aimed to evaluate the psychometric characteristics of the Turkish version of the "Stress Scale for Siblings of Childhood Cancer Patients (SCCP)".

Methods: This study was conducted with 273 siblings aged 11-16 of childhood cancer patients (SCCPs) who were treated in a hospital in the Black Sea Region of Türkiye between March 2022 and April 2024. Data were collected with "The Sociodemographic Information Form" and "SCCP".

Examining the effect of virtual reality application on pain and anxiety in the care of chronic wounds on the leg.

Background: In recent years, virtual reality applications have begun to be used in many areas of the healthcare (education, treatment, etc.). It has been observed that it reduces pain and anxiety by distracting individuals during painful procedures.

Structure of the Outer Membrane Transporter FemA and Its Role in the Uptake of Ferric Dihydro-Aeruginoic Acid and Ferric Aeruginoic Acid in .

Iron is essential for bacterial growth, and synthesizes the siderophores pyochelin (PCH) and pyoverdine to acquire it. PCH contains a thiazolidine ring that aids in iron chelation but is prone to hydrolysis, leading to the formation of 2-(2-hydroxylphenyl)-thiazole-4-carbaldehyde (IQS). Using mass spectrometry, we demonstrated that PCH undergoes hydrolysis and oxidation in solution, resulting in the formation of aeruginoic acid (AA).

A Novel and Promising Method for Prediction of Early Surfactant Requirement in Preterm Infants With Respiratory Distress Syndrome: Pulmonary Near-Infrared Spectroscopy.

Introduction: Non-invasive monitoring techniques have been used more commonly in neonatal clinical practice. The aim of this study was to evaluate the role of lung near-infrared spectroscopy (NIRS) for determination of the severity of Respiratory Distress Syndrome (RDS) and the requirement of surfactant therapy in preterm infants.

Methods: A total of 60 preterm infants with RDS were evaluated in terms of the requirement of surfactant therapy, as surfactant group (SG) or no-surfactant group (CG).

Comparison of two different intraocular lenses used in the modified Yamane technique.

Purpose: To compare AcrySof MA60AC (Alcon Laboratories, Fort Worth, TX, USA) and Sensar AR40e (Johnson and Johnson, Santa Ana, CA, USA) used in Yamane sutureless scleral fixation technique in terms of visual acuity, refractive stability, and complications.

Methods: A retrospective, cross-sectional study was conducted in Istanbul Başakşehir Çam and Sakura City Hospital. Patients were divided into two groups: The first group consisted of patients with MA60AC lenses, while the second group consisted of patients with AR40e.

The association between blood sodium levels and survival in patients treated with immune checkpoint inhibitors.

Background: Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for solid tumors, offering substantial survival benefits. Despite this progress, many patients do not achieve durable responses, highlighting the need for novel prognostic biomarkers. This study investigates the association between serum sodium levels and survival outcomes in patients treated with ICIs.

The Effects of Peruvian maca () Root Extract on In Vitro Cultured Porcine Fibroblasts and Adipocytes.

Peruvian maca () is a plant known for its nutritional and medicinal properties whose use as a supplement in animal diets has attracted much interest. We studied the effects of powdered maca root extract on the growth potential of in vitro cultured porcine cells prior to its use as an additive in animal nutrition. Fibroblast cell viability (MTT), cell proliferation (BrdU), and apoptosis level (TUNEL) were measured for a range of extract doses (0, 0.

Evaluation of the Effect of Management of Drug-Related Problems on Clinical Outcomes of Pulmonary Embolism Outpatients: A Randomized Controlled Trial.

Pulmonary embolism (PE) poses significant morbidity and mortality risks, necessitating tailored anticoagulant therapy. Limited studies investigate the drug-related problems (DRPs) in PE. This study aims to evaluate the impact of clinical pharmacist (CP) interventions on drug-related problems (DRPs) and clinical outcomes in outpatients with PE.

The Effect of a Working Memory Intervention Package on the Working Memory Performance of Primary School Students with Specific Learning Disabilities.

This study examines the effects of a working memory (WM) intervention package on the WM performance of students with Specific Learning Disabilities (SLDs). A pre-test post-test experimental design was applied with 40 students, divided equally into experimental (20 students) and control groups (20 students). Data were collected using the Working Memory Scale (WMS), Raven's Standard Progressive Matrices (RSPM), and the Working Memory Performance Tasks Form (WM-PTF).

Modified cachexia index and survival in metastatic breast cancer patients treated with CDK 4-6 inhibitors.

Background: The objective of this study is to evaluate the correlation between survival outcomes and the modified cachexia index (mCXI) in patients with metastatic breast cancer who have been treated with cyclin-dependent kinase (CDK) 4/6 inhibitors.

Methods: This study was conducted on patients with metastatic breast cancer who received CDK 4/6 inhibitors (either Palbociclib or Ribociclib) between January 2020 and November 2024.

Results: 240 patients were included.

Surgical results of liver metastases of tumors other than colorectal-neuroendocrine: Is it really worth it or is it necessary?

Objectives: It is known that surgical treatment is advantageous in terms of efficacy and survival in colorectal cancer and neuroendocrine tumor liver metastases. Our aim in this study was to determine the results of surgical treatment of non-colorectal (NCR), non-neuroendocrine tumor (NNET) liver metastases (LM).

Material And Methods: A total of 125 patients having NCR and NNET were included in the study.

Prediction of hypertensive responses associated with interscalene block, a prospective cohort study.

Background: The aim was the effects of interscalene block (ISB) on blood pressure, focusing on identifying anatomical and clinical predictors of hypertensive responses. The aim is to improve the safety and effectiveness of ISB, especially in patients at increased risk of adverse hemodynamic events.

Methods: We conducted a prospective cohort study including patients undergoing ISB.

The prevalence of incontinence and its impact on quality of life.

The study set out to find out how common urine incontinence was in the community and how it affected people's quality of life and other relevant characteristics. Patients who applied to Family Medicine Outpatient Clinics were asked to complete a questionnaire as part of the study. Participants who consented to participate in the study were given access to a questionnaire that included the Incontinence Quality of Life Scale (I-QOL), the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF), and the Three Incontinence Questions (3IS) form.

Management of acute calculous cholecystitis in the emergency department: Evaluating the role of laboratory and radiological findings in a retrospective study.

Background: Acute calculous cholecystitis (ACC) is a significant cause of acute abdominal pain, accounting for 90-95% of gallbladder inflammations caused by gallstones. Its clinical presentation ranges from nonspecific abdominal pain to septic conditions associated with an acute abdomen. Timely and accurate diagnosis is critical in patient management, as delayed diagnosis or inadequate treatment can result in increased morbidity and life-threatening complications such as perforation or biliary peritonitis.

Profiling of organic and inorganic impurities in seized methamphetamine samples from Ankara, Türkiye: A chemometric implication in forensic chemistry.

The forensic profiling of methamphetamine impurities offers critical insights into synthetic routes, geographic origins, and trafficking networks associated with illicit drug production. In this study, organic and inorganic impurities in methamphetamine samples seized in Ankara, Türkiye, were analyzed using a comprehensive chemometric approach, including Principal Component Analysis (PCA), Hierarchical Cluster Analysis (HCA). Organic impurities were detected through Gas Chromatography-Mass Spectrometry (GC-MS), while Inductively Coupled Plasma Mass Spectrometry (ICP-MS) was employed to identify trace metals (Al, As, Au, Ba, Cr, Cu, Fe, Mn, Mo, Pb, Sb, Sn, V, Zn).

Effect of post-curing parameters and material thickness on the color stability of 3D-printed dental resins: An in vitro study.

Objective: To assess the effect of variations in post-curing temperatures and times on the colour stability of 3D-printed resins used in orthodontics and paediatric dentistry applications and the effect of material thickness on colour properties was also examined.

Methods: The two different disk samples (15.00×1.

Enhancing Immersion in Virtual Reality-Based Advanced Life Support Training: Randomized Controlled Trial.

Background: Serious game-based training modules are pivotal for simulation-based health care training. With advancements in artificial intelligence (AI) and natural language processing, voice command interfaces offer an intuitive alternative to traditional virtual reality (VR) controllers in VR applications.

Objective: This study aims to compare AI-supported voice command interfaces and traditional VR controllers in terms of user performance, exam scores, presence, and confidence in advanced cardiac life support (ACLS) training.

High-performance electroadhesive clutches with multilayered architecture.

Electroadhesive (EA) clutches are promising for advanced motion and force control in robotics, haptics, and rehabilitation, owing to their compactness and light weight. However, their practical use is limited by the inability to deliver high forces at low voltages, primarily due to a lack of understanding of their mechanics. We introduce a novel deformable body fracture mechanics approach and high-resolution strain field imaging to reveal that nonuniform stress distributions cause EA clutches to fail through delamination and crack propagation.