Impact of monosodium glutamate-induced obesity on learning, memory, and DNA damage: sex-based comparative study in rats.

Obesity is a global health crisis linked to numerous adverse outcomes including cardiovascular disease, type 2 diabetes, cancer and cognitive decline. This study investigated the sex-specific effects of monosodium glutamate (MSG)-induced obesity on learning, memory, anxiety-like behavior, oxidative stress, and genotoxicity in rats. In 32 neonatal Wistar albino rats, subcutaneous MSG injections were administered to induce obesity.

Fronto-orbital advancement: Comparison of syndromic and nonsyndromic craniosynostosis patients.

Craniosynostosis causes functional and aesthetic problems that require fronto-orbital advancement in patients to correct the cranial deformity and to prevent functional problems due to increased intracranial pressure (ICP). In this study, demographic information, operative details, preoperative clinical findings, and postoperative outcomes were reviewed for 106 craniosynostosis patients with at least 1 year of follow-up. Many factors such as functional losses due to increased ICP before surgery, resynostosis, fronto-orbital relapse, surgical complications and aesthetic results were compared in syndromic and non-syndromic patients.

The Effect of Providing Video-Animated Information to Female Patients With Stress Urinary Incontinence Before the Urodynamic Study on the Patient's Anxiety, Pain, Satisfaction, and Willingness to Repeat the Procedure.

Objectives: To investigate the effect of providing video-animated information to female patients with stress urinary incontinence before urodynamics on the patient's anxiety, pain, satisfaction, and willingness to repeat the procedure.

Methods: Before the procedure, patients were divided into two groups with 1:1 randomization. While one group was given written and verbal information, the other group was additionally given animated video information accompanied by a doctor.

Increasing microplastics pollution: An emerging vector for potentially pathogenic bacteria in the environment.

Microplastics (MP), plastic particles <5 mm, are of global concern due to their worldwide distribution and potential repercussions on ecosystems and human well-being. In this study, MP were collected from the urbanized Susurluk basin in Türkiye to evaluate their vector function for bacterial biofilms, both in the wet and dry seasons. Bacterial biofilms were predominantly found on polyethylene (PE), polypropylene (PP), and polystyrene (PS), which constitute the most common MP types in the region.

in Major Depression: Possible Association of and with Childhood Traumas.

Objective: Psychosocial and genetic factors are considered to play roles in the etiological mechanisms of major depressive disorder (MDD). The involvement of miRNAs in the etiopathogenesis of depression and childhood traumas is still unclear. This study aims to reveal potential differences in miRNA levels between patients with depression and healthy individuals and assess their connection to childhood traumas.

Prevalence of Pancreatic Steatosis in Inflammatory Bowel Disease Patients.

Objectives: Inflammatory bowel diseases (IBD) are chronic, immune-mediated disorders of the gastrointestinal system. Pancreas can be affected in IBD patients with a wide array of clinical conditions including acu-te pancreatitis, abnormalities of pancreatic duct and pancreatic insufficiency. Pancreatic steatosis (PS) is an important but often overlooked pathology of pancreas.

Rhizopogon luteolus and Ganoderma adspersum Extracts Inhibit Invasion through the Crosstalk between Anti-oxidant Activity and Apoptosis Induced by pAKT/Rb.

Objective: Lung cancer is the primary cause of cancer-related deaths globally. Protein kinase B (AKT) protein is associated with many pathways in non-small cell lung cancer (NSCLC), such as proliferation, migration, invasion, and apoptosis. Mushrooms have a long history of being used in traditional medicine to treat various diseases.

Synthesis, characterization, and investigation of photochemical and in vitro properties of novel Zn(II) phthalocyanine.

A new nonperipheral zinc(II) phthalocyanine bearing octa carboxylic acid ethyl ester derivative substituted triazole attached propylmercaptothiobenzylmercapto derivative was synthesized via the tetramerization reaction of phthalonitrile. The photochemical in vitro photodynamic activity of zinc(II) phthalocyanine (), such as human nonsmall cell lung carcinoma cell lines, was investigated in this study. The singlet oxygen generation property of novel zinc(II) phthalocyanine () was also examined due to the significantly high singlet oxygen quantum yield of (F = 0.

Deeply Saddening Life Events Play a Carcinogenic Role by Inducing Mutations in and Genes.

Background/objectives: In the past few decades, many studies have been conducted to find out that psychological stress and cancer are closely linked. Moreover, it was reported that stress can induce mutations in gene level. Therefore, in this study we want to examine a relationship between stressful life events, gene mutation and cancer.

The ability of the prognostic nutritional index to predict short-term mortality in geriatric acute heart failure.

Background: Heart failure is a critical cardiovascular condition, necessitating comprehensive treatment approaches and contributing to elevated mortality rates. This study aimed to evaluate the effect of the prognostic nutritional index (PNI) on the prognosis of geriatric patients diagnosed with acute heart failure.

Results: A total of 104 patients were included and evaluated retrospectively in this study; 57.

Transition of patients with systemic lupus erythematosus from pediatric to adult-oriented rheumatology care.

Background/aim: The transition from pediatric to adult-oriented care for individuals with juvenile-onset systemic lupus erythematosus (SLE) poses significant challenges. This study aimed to assess the outcomes of transitioning patients with juvenile-onset SLE from pediatric to adult-oriented care.

Materials And Methods: Patients with juvenile-onset SLE were included in the study.

Early discharge with elevated C-reactive protein levels is safe after endoscopic-assisted coronary bypass grafting: Optimisation of postoperative care.

Objective: This study describes the perioperative kinetics of C-reactive protein in patients undergoing endoscopic coronary artery bypass grafting for single target vessel left anterior descending disease, with early postoperative discharge.

Methods: From July 2021 to April 2024, patients were included in this single-centre retrospective study ( = 208), excluding C-reactive protein-modulating complications. Perioperative and 14-day follow-up C-reactive protein levels and clinical signs of infections were analysed.

A review of nomenclature in minimally invasive coronary artery bypass grafting-the anarchy of terminology.

Objectives: Since the development of minimally invasive coronary surgery, nomenclature has rapidly grown to distinguish each unique method. The goal of this review was to provide a comprehensive overview of the different terms used for minimally invasive coronary bypass grafting through the years.

Methods: A literature search was performed in August 2024 using the PubMed electronic database.

Replacement of a single-tooth implant restoration with the abutment dual-scanning technique: a case report.

Background: Digital technologies have not only revolutionized workflow strategies for implant- supported fixed prostheses but also changed preferences in the choice of restoration retention. Owing to the effortlessness of developing workflows with digitalization, screw-retention has become favored for initial prostheses. However, cement retention is still indicated for cases in which abutment reuse is needed for replacing failing restorations with technical complications.

Spiritual Meaning Making and Trauma Recovery: Evaluation of a Psycho-social Intervention for Earthquake Survivors in Turkey.

This study sets out to develop a psycho-social model for assessing the effectiveness of spiritually oriented logotherapy for earthquake victims with PTSD following the 6 February 2023, Kahramanmaraş earthquake in Turkey. The findings of this study will undoubtedly contribute to the development of post-disaster spiritual support services. We developed and implemented a six-week "Psycho-Social Training Programme through Spiritually Oriented Meaning" in the cities of Malatya, Elazığ and Kahramanmaraş, which were significantly affected by the earthquake.

Efficacy of Low-Dose Ketamine and Propofol in the Treatment of Experimental Refractory Status Epilepticus on Male Rats.

Refractory status epilepticus (RSE) is a condition with serious mortality and morbidity rate, resistant to benzodiazepine and second-line antiepileptic drugs. This study aimed to electrophysiologically investigate the combination of NMDA receptor antagonist ketamine and GABAergic agent propofol in an RSE model induced by lithium-pilocarpine in male Sprague-Dawley rats. Seventy-two male Sprague-Dawley rats were divided into nine groups.

Post-earthquake spiritual well-being and depression levels of postpartum women in Turkey.

This study was carried out to examine the spiritual well-being and depression levels of postpartum women following the two major earthquakes that occurred in 2023 with the epicenter Kahramanmaraş in Turkey. This cross-sectional analytical study was conducted with the participation of 345 postpartum women admitted to the maternity ward of a medical faculty hospital in the provincial center of Kahramanmaraş in Turkey between June and September 2023. Data were collected using the Spiritual Well-Being Scale (SWBS) and the Edinburgh Postnatal Depression Scale (EPDS).

Endoscopic-Assisted Multivessel Off-Pump Coronary Artery Bypass Grafting: Experience of the First 100 Procedures.

Background: This study presents an overview of our technique and the perioperative outcomes for the first 100 patients who underwent minimally invasive endoscopic-assisted off-pump multivessel bypass grafting (endoscopic coronary artery bypass [endo-CAB]) at the Catharina Hospital in Eindhoven.

Methods: The first 100 patients undergoing multivessel endo-CAB from May 2022 to March 2024 were included in this retrospective, single-center, observational study (N=100). The study encompassed both elective and urgent surgical revascularization.

Endoscopic-assisted, minimally invasive versus sternotomy total arterial multivessel bypass grafting.

Objectives: This single-centre study compared the perioperative outcomes after total arterial multivessel revascularization through endoscopic-assisted, minimally invasive surgery compared to a conventional sternotomy approach.

Methods: In this retrospective, propensity score-matched (PSM) cohort study, a total of 740 patients were analysed [endoscopic coronary artery bypass grafting (Endo-CAB), N = 92; Sternotomy, N = 648]. After PSM (1:2 ratio), 73 Endo-CAB and 137 sternotomy patients were compared with an equal number of distal anastomoses (Endo-CAB 2.

Effectiveness of health literacy-based motivational interviewing and health education on adolescents' nutrition and exercise behaviors in Turkiye: A randomized controlled trial.

Objective: To measure the effectiveness of health literacy-based motivational interviewing and health education to improve adolescents' nutrition and exercise behaviors.

Study Design: A randomized controlled trial.

Methods: The study was completed with 63 adolescents (aged 14-15 years) of which 21 were in the motivational interviewing group, 21 were in the health education group, and 21 were in the control group.

Physical Symptoms and Coping Strategies With Earthquake Stress Among Adults Living in Tent Cities: A Cross-Sectional Study.

Aim: This study aimed to examine the physical symptoms, coping strategies for earthquake stress and factors predicting coping strategies among adults staying in tent cities after an earthquake.

Design: A cross-sectional design was conducted.

Methods: The study sample consisted of 706 adults residing in tent cities in three cities of earthquake-affected regions.

The Efficacy of Glecaprevir/Pibrentasvir in Chronic Hepatitis C Patients and the Impact of the COVID-19 Pandemic: Multicenter Real-Life Data.

Objective: This study aimed to demonstrate the real-life efficacy and safety of glecaprevir /pibrentasvir in the treatment of chronic hepatitis C, as well as to identify the problems caused by the COVID-19 pandemic in the follow-up and treatment of patients.

Materials And Methods: The study was conducted retrospectively with the participation of researchers from universities or training and research hospitals. It included patients with chronic hepatitis C who were over 18 years of age, treatment-naïve or treatment-experienced, had detectable HCV RNA and were receiving glecaprevir/pibrentasvir treatment.