Publications by authors named "Muegen Baykan"

Introduction: Invagination is a rare cause of mechanical intestinal obstruction in adults, but half of their causes are malignant. A diagnosis of invagination in an adult patient strongly suggests presence of a malignant pathology. Moreover some benign conditions may resemble malignant disorders like inflammatory fibroid polyp.

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Hydatidosis is an endemic illness in many regions of world. Several serodiagnostic techniques have been evaluated for the diagnosis of cystic hydatid disease caused by Echinococcus granulosus. The aim of this study was to assess the efficiency of the commercial fluorescent antibody test (IFAT), indirect hemaglutination test (IHAT) and in-house IFA tests.

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It is well known the relationship between oxidative stress and vascular function. However, association between total antioxidative capacity and arterial stiffness was not studied in patients with hypertension (HT). This study investigated whether total antioxidative capacity is associated with arterial stiffness and wave reflections.

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The incidence of anomalous coronary artery is approximatly 1% in patients who undergo coronary angiography. These anomalies, together with congenital heart disease, may cause myocardial ischemia, decreased life expectancy and sudden death. The case of a patient with a rare anomalous right coronary artery (RCA) from the very proximal part of the left anterior descending (LAD) artery via a collateral, aberrant vessel is described.

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Background: The aim of this study was to assess left ventricular (LV) function and the Tei index by tissue Doppler imaging (TDI), and also to evaluate the relationship of thrombolysis in myocardial infarction (TIMI) frame count (TFC) with the Tei index and LV function in patients with slow coronary flow (SCF).

Methods: We prospectively evaluated 50 patients with SCF and 27 control subjects. Diagnosis of SCF was made by TFC.

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Background: Hypothyroidism has a large number of adverse effects on the cardiovascular system such as impaired cardiac contractility. Left ventricular (LV) asynchrony is defined as loss of the simultaneous peak contraction of corresponding cardiac segments.

Objective: To assess systolic asynchrony in patients with overt hypothyroidism.

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Neuroblastoma (NB) is a challenging malignancy of the sympathetic nervous tissue characterized by a very poor prognosis. One important marker for NB is the expression of tyrosine hydroxylase (TH), the first-step enzyme of catecholamine biosynthesis. We could show stable and high TH gene expression in 67 NB samples independent of the clinical stage.

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The aim of this study was to report the intermediate follow-up results of stent implantation for coarctation of the aorta in children from Turkey. Patients with native or postoperative coarctation, who had abnormal flow at the descending aorta exceeding diastolic phase on Doppler echocardiography or upper extremity hypertension, underwent endovascular stent implantation. Ten patients with a mean age of 12.

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Objective: The evidence of structural and functional cardiac abnormalities has been demonstrated by echocardiography in patients with chronic kidney disease (CKD). This study investigated whether left ventricular (LV) asynchrony is present in patients with CKD and normal QRS duration.

Methods: Tissue synchronization imaging (TSI) was performed in 25 (56 +/- 14 years) patients with CKD and narrow QRS complexes and 25 (51 +/- 12 years) control subjects.

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Our aim was to assess the associations of temporal lobe epilepsy (TLE) and idiopathic generalized epilepsy (IGE) with comorbid psychiatric conditions, especially obsessive-compulsive disorder (OCD), in a comparative design. We evaluated 29 patients with TLE, 27 patients with IGE, and 30 healthy controls. The Structured Clinical Interview for DSM-IV (SCID), Yale-Brown Obsessive Compulsive Scale (Y-BOCS) Symptom Checklist, and Beck Depression Inventory (BDI) were administered.

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Background/aims: Atrial fibrillation (AF) is common among hemodialysis (HD) patients and is associated with high mortality. P wave dispersion (PWD) is a noninvasive electrocardiographic marker of paroxysmal AF. Our aim was to evaluate the effect of HD session on PWD.

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Objective: To evaluate seroprevalences of hepatitis B and C viruses, human immunodeficiency virus (HIV), and syphilis infections among engaged couples.

Methods: This is a cross-sectional study of all engaged couples enrolled at 20 Health Centers and one Maternity Center of Sivas Health Directorate between May and September 2005 in Sivas, a central Anatolian city, in Turkey. Seroprevalances of hepatitis B (HB) surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs), anti-hepatitis C virus (HCV), anti-human immunodeficiency virus (anti-HIV), and syphilis was assessed.

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Background: The role of endogenous relaxin on hypertensive cardiovascular damage remains unknown. We investigated the relaxin level and its relation to cardiovascular function in patients with never treated hypertension (HT).

Methods: We studied 42 (47.

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Objective: The aim of this study was to assess flow-mediated dilatation (FMD) of the brachial artery in patients with acromegaly.

Subjects And Methods: We prospectively evaluated 25 patients with acromegaly (14 females, 11 males; aged 42 +/- 12 years; growth hormone (GH) levels 34 +/- 14 ng/ml) and 27 control subjects (15 females, 12 males; aged 45 +/- 8 years; GH levels 3 +/- 1.5 ng/ml).

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The inhibitor of apoptosis protein survivin is highly expressed in neuroblastoma (NB) and survivin-specific T cells were identified in Stage 4 patients. Therefore, we generated a novel survivin minigene DNA vaccine (pUS-high) encoding exclusively for survivin-derived peptides with superior MHC class I (H2-K(k)) binding affinities and tested its efficacy to suppress tumor growth and metastases in a syngeneic NB mouse model. Vaccination was performed by oral gavage of attenuated Salmonella typhimurium SL7207 carrying pUS-high.

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The effects of local 17beta-oestradiol therapy on the vaginal mucosa and endometrial thickness were studied in 35 post-menopausal women with symptoms of vaginal atrophy. Signs and symptoms of vaginal atrophy were measured by anamnesis, visual examination and the maturation index before and after 12 weeks' treatment with 17beta-oestradiol in the form of vaginal tablets. The maturation proportion on vaginal smear, endometrial thickness on transvaginal ultrasonography and plasma concentrations of follicle-stimulating hormone, luteinizing hormone and oestradiol were also determined.

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Purpose: To investigate the focal interictal EEG abnormalities in adult patients with absence seizures (ASs) and to identify their clinical, EEG and semiological correlates.

Methods: Fifty patients older than 18 years, diagnosed as having IGE with AS documented with ictal recordings. Interictal focal sharp or spike-waves and strictly focal paroxysmal slow activity were considered as focal EEG features.

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To determine the factors that affect milk iron content at the second week of lactation and whether the supplementation to lactating mother with iron might increase breast milk iron content between 2 weeks and 4 months postpartum. Healthy mothers were enrolled 10 to 20 days postpartum, if their babies were term, normal gestational age, and exclusive breastfed. Maternal blood samples for hemoglobin (Hb), iron, iron binding capacity, serum ferritin, and breast milk samples for iron and zinc were taken and mothers were randomized into iron supplemented and placebo groups.

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In children with spasticity, deep tendon reflexes are hyperactive and even stimulation of normal dorsal rootlets can produce exaggerated full-strength, single-twitch responses in the muscles they innervate. This phenomenon is called the brisk hyperactive response (BHR). The aim of this study was to compare the efficacy of 2 volatile anesthetics, isoflurane and sevoflurane, for suppressing the confounding effect of BHR during selective dorsal rhizotomy (SDR) in children with spasticity.

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Background: Non-convulsive status epilepticus (NCSE): a condition that may be associated with different levels of altered consciousness without any apparent motor signs. There are published reports that it may be associated with antibiotic use patients with renal failure.

Method: This is a retrospective analysis of our 12 NCSE (2 men, 10 women, a mean age: 58.

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We have recently evaluated a 54-year-old woman who had migraine without aura in her history but presenting with a typical hypnic headache (HH) which is presumably not a primary headache but associated with an ergotamine overuse headache. Her HH was relieved with a washout protocol which includes 75 mg amitriptyline daily with the addition of metoclopramide and encouraging her not to use any analgesics. Our aim was to report this unique patient to emphasize this rare association and to discuss the possible pathophysiological implications for both of these entities.

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The infection rate of Enterobius vermicularis was investigated in 1,070 preschool children aged 5-7 years in Kayseri, Turkey by cellotape anal swab from May-September 2005. The children's parents were asked to complete questionnaires inquiring into the potential risk factors involved. The overall egg positive rate for E.

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Purpose: Our aim was to investigate the [(1)H] MR spectroscopy (MRS) findings of Lafora Disease (LD), which is a disabling form of progressive myoclonic epilepsy.

Methods: Twelve patients diagnosed with LD and 12 control subjects underwent MRS studies with single-voxels of 8 cc obtained in the frontal lobe, pons, and cerebellum. The metabolites and NAA/Cr, NAA/Cho, Cho/Cr, mI/Cr ratios were calculated.

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Rheumatic fever is the main etiology for valvular heart diseases in children. Valvular insufficiencies are frequent, and development of disease at an earlier age results in severe valvular damage. In this report we present a 9-year-old child with rheumatic heart disease who was admitted to our clinic with hemoptysis and haematemesis caused by mitral stenosis (MS) resulting in pulmonary venous hypertension.

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Background: Aortic stiffness is an independent risk factor for cardiovascular events and mortality. The measurement of pulse-wave velocity (PWV) is the most simple, noninvasive, and robust method to determine aortic stiffness. Whether aortic stiffness contributes to aortic valve sclerosis (AVS) remains unknown.

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