Teachers' perceptions of children with autism spectrum disorder: a comparison between special education and preschool teachers.

This study aimed to determine the metaphors preschool and special education teachers developed about autism. In this study, the researchers used the phenomenology design, one of the qualitative research designs. While determining the study group of the research, the convenience sampling method, one of the purposeful sampling methods, was used.

Does Helicobacter pylori have a role in the pathogenesis of otitis media with effusion, or is it a fallacy??

Purpose: Helicobacter pylori, causing chronic systemic infection, may colonize in middle ear milieu and conduce to effusion collection. Many investigations on relationship between pathogenesis of otitis media with effusion (OME) and Helicobacter pylori yielded conflicting results. We investigated Helicobacter pylori presence in effusion and adenoid samples of children having OME and in middle ear and adenoid samples of children with healthy middle ears to elucidate its role on OME pathogenesis.

ONCOllab for Transmission of Knowledge Related to Oral Complications of Cancer Therapy Among Dental Students.

Introduction: ONCOllab is a social media application developed by FDI to improve the management of oral complications that may arise during cancer therapy. This study aimed to evaluate the effects of ONCOllab on learning and perception among dental students.

Material And Method: A theoretical test on oral complications of cancer therapy to determine baseline level knowledge was given to fourth-year dental students.

Investigation of the effect of a virtual reality-based imagery training model on muscle activation in athletes.

Introduction: In the field of sports psychology, imagery training plays a significant role in enhancing athletes' mental preparation and optimizing sports performance. This study aims to investigate the effects of the Virtual Reality-Based Imagery (VRBI) training model on muscle activation and kinesthetic motor imagery skills in athletes. Specifically, the study compares the VRBI model with traditional imagery methods, including Visual Motor Behavior Practice (VMBP) and Video Modeling (VM), to determine its effectiveness in improving neuromuscular responses.

Caffeine use in preterm neonates: national insights into Turkish NICU practices.

Objective: Caffeine is a proven medication used for the prevention and treatment of apnea in premature infants, offering both short- and long-term benefits. International guidelines provide a range of recommendations regarding the preterm population eligible for caffeine prophylaxis, including the timing, dosage, and duration of treatment. Our national guidelines, published prior to the most recent updates of the international guidelines, recommend the use of caffeine citrate starting from the first day after delivery for preterm infants with a gestational age of <28 weeks.

Measuring Total Metabolic Tumor Volume from F-FDG PET: A Reality Check.

Measuring total metabolic tumor volume (TMTV) on F-FDG PET/CT images in clinical practice requires a fast, reliable, and easy-to-perform multilesional segmentation workflow. We conducted a field test to derive total metabolic volumes using 5 representative baseline F-FDG PET/CT scans from patients with diffuse large B-cell lymphoma. The scans were transferred to 10 different sites or readers who used different commercially available software platforms to derive TMTV after a recently proposed benchmark workflow.

Anagen Effluvium in a Child Misusing Methotrexate: A Case Report With Dermoscopic Findings.

Anagen effluvium is a rare adverse effect of methotrexate therapy, generally associated with high-dose regimens. We report a 12-year-old girl who developed abrupt hair loss 1 week after inadvertently taking methotrexate 15 mg daily for five consecutive days (total 75 mg), without other signs of systemic toxicity. Trichoscopic examination and trichogram findings confirmed methotrexate-induced anagen effluvium, and spontaneous hair regrowth occurred after 2 months.

The Role of Gene Expression and Serum Adropin Levels in Patients with Familial Mediterranean Fever.

Familial Mediterranean Fever (FMF) is a genetic autoinflammatory disease primarily affecting populations in the Mediterranean region. The pathogenesis of FMF and the roles of various molecules remain unclear. Adropin, a protein encoded by the Energy Homeostasis-Associated Gene (), is involved in energy metabolism and inflammation.

Classification of FAMACHA© Scores with Support Vector Machine Algorithm from Body Condition Score and Hematological Parameters in Pelibuey Sheep.

The aim of this study is to evaluate the model performance in the classification of FAMACHA© scores using Support Vector Machines (SVMs) with a focus on the estimation of the FAMACHA© scoring system used for early diagnosis and treatment management of parasitic infections. FAMACHA© scores are a color-based visual assessment system used to determine parasite load in animals, and in this study, the accuracy of the model was investigated. The model's accuracy rate was analyzed in detail with metrics such as sensitivity, specificity, and positive/negative predictive values.

Comparative Analysis and Validation of the IMPEDED VTE, IMPEDE VTE, and SAVED Risk Models in Predicting Venous Thromboembolism in Multiple Myeloma Patients: A Retrospective Study in Türkiye.

Several thrombotic risk assessment models have been proposed for identifying patients with a high risk of thrombosis (the IMPEDE venous thromboembolism (VTE), SAVED, and PRISM scores) in multiple myeloma (MM). Recently, adding a biomarker (D-dimer) for the IMPEDE VTE score has shown that it can boost the detection power of IMPEDED VTE. However, data from studies comparing these models in MM are scarce.

Factors predicting local or systemic side effects related to intravesical BCG (Bacillus Calmette-Guérin) therapy: a retrospective observational study.

Objective: Intravesical BCG treatment is the most frequently preferred adjuvant treatment option with its effective results in non-muscle invasive bladder tumors. Despite effective results, systemic and local side effects can be observed and can be one of the main reasons for treatment discontinuation. In this study we aimed to identify clinical factors predicting BCG-related side effects during intravesical BCG therapy in patients with non-muscle invasive bladder cancer.

Design, synthesis, and biological evaluation of novel amidoxime or amidine analogues of some 4-anilino-6,7-dimethoxyquinazolines with a potent EGFR inhibitory effect.

A series of 6,7-dimethoxy-4-anilinoquinazoline derivatives, which have amidine (4a-4d, 5a-5c, 6a-6d) and amidoxime (4e, 5d, 6e) moieties, were synthesized and evaluated their anticancer activity on various cancerous cell lines (H1975, HCC827, and H23). Among the synthesized compounds, 4c was found to be the most potent inhibitor of EGFR, comparable to erlotinib, with higher than 10 μM EC values for H1975 and H23 and 0.16 μM EC value for HCC827 cells.

Environmental hazards of light cigarette butts and filters: physiological, cytotoxic, and genotoxic assessment using the Allium cepa L. assay.

Cigarette butts are a common form of litter that pose significant ecological risks due to their toxic components, which can accumulate in soils, impacting human health, plant growth, and soil-dwelling organisms. This study investigated the environmental implications of "light" cigarette butts, which, like regular ones, contain harmful chemicals that render them hazardous waste. The cellulose acetate filters are notably resistant to biodegradation, allowing them to persist in the environment and leach toxins.

Epidural volume extension versus dural puncture epidural analgesia for labor: A prospective randomized study.

Background: Providing effective labor analgesia is very important for maternal and infant safety. Various neuraxial techniques are used for this purpose. Our objective was to compare the epidural volume extension (EVE) and dural puncture epidural (DPE) procedures employed in clinical practice for labor analgesia, focusing on labor parameters, pain levels, fetal outcomes, and complications.

Effect of Progressive Relaxation Exercises on Dyspnea and Comfort Level in Individuals With Chronic Obstructive Lung Disease: A Randomized Controlled Study.

This parallel-group randomized controlled trial aimed to investigate the effect of progressive relaxation exercises on dyspnea and comfort level in individuals with chronic obstructive pulmonary disease. The study utilized a stratified and block randomization methodology, with 42 patients completing the trial. Patients in the intervention group received 30-min progressive relaxation exercises for 6 weeks.

Klebsiella pneumoniae infections in the intensive care unit: risk factors related to carbapenem resistance and mortality.

Introduction: Nosocomial infections caused by carbapenem-resistant Klebsiella pneumoniae in intensive care units (ICUs) are increasing worldwide. Morbidity and mortality rates are quite high in these infections due to limited treatment options and various risk factors. We determined the rate of carbapenem resistance, risk factors for carbapenem resistance, mortality rate, and risk factors associated with mortality in nosocomial infections in the adult ICU.

Investigating the impact of feature extraction methods on prediction accuracy of neurological recovery levels in comatose patients post-cardiac arrest.

Cardiac arrest can cause irreversible Post-Cardiac Arrest Brain Injury (PCABI), but predicting PCABI with certainty remains challenging. This study aims to improve prognostication by predicting neurological recovery using EEG data from the 'I-CARE: International Cardiac Arrest Research Consortium Database.' Data were preprocessed with an FIR Equiripple Bandpass Filter, and three feature extraction methods were applied.

Advanced Functional Polymers: The Role of Tyrosine-Coumarin Modifications in Optical and Electrical Performance.

Advanced functional polymeric materials can possess chemical reactivity, catalytic properties, photosensitivity, electrical conductivity, biological activity, biocompatibility, pharmacological properties, selective separation, and energy conversion of traditional polymers. Because of these properties, the production and characterization of functional polymers has become an essential part of modern industry and advanced technology. Methacrylate polymers are highly versatile materials owing to their exceptional properties including superior optical transparency, excellent light transmission, and robust thermal stability.

Lung involvement in patients with psoriatic arthritis.

Objectives: The study aimed to describe the prevalence and patterns of pulmonary lesions in the patients with psoriatic arthritis (PsA).

Patients And Methods: Pulmonary symptoms and thorax imaging findings of 247 patients (155 females, 92 males, mean age: 52.0±12.

Matrix preparation and workflow for microplastics analysis in soil.

One of the main difficulties in microplastic (MP) research is the lack of standardized, real-world methods such as matrix blank and simultaneous tracking of polymer particles for enumeration. Building on a previous study, a matrix preparation and experimental workflow for soil matrices is presented that addresses the challenges of purification to allow subsequent analysis using Nile Red-stained MPs as a surrogate. Key steps include peroxide digestion and density separation (NaI) followed by centrifugation for low density polyethylene (LDPE) and polyvinyl chloride (PVC) surrogates to assess recoveries in terms of number and size, based on fluorescence microscopy and Raman spectroscopy.

Challenges of Drug Testing in Addiction Treatment: A Case Report of Protracted Fentanyl Clearance in a Patient Involved With Child Protective Services and Probation.

Fentanyl, a potent synthetic opioid, has been linked to an increasing number of overdose deaths in the United States. It began replacing heroin in the illicit drug supply in 2013, and now contributes to both drug-related criminal offenses and the need for treatment. Its unique pharmacokinetics complicate the role of drug testing, which is a ubiquitous practice in both criminal justice and treatment settings.

Might be over-evaluated: Predicting choledocholithiasis in patients with acute biliary pancreatitis.

Background: The increase in liver cholestasis enzyme and bilirubin levels, especially due to pancreatitis, mimics choledocholithiasis. This study aimed to examine the relationship between demographic and laboratory cut-off values and the presence of choledocholithiasis in patients with acute biliary pancreatitis (ABP).

Methods: Patients diagnosed with ABP in the Department of General Surgery at Istanbul Faculty of Medicine between January 2010 and December 2022 were retrospectively analyzed.

Two Interesting Findings in One Case: Xanthogranulomatous Inflammation of the Colon and Isolated Widespread Liver Metastasis of Prostate Cancer on 68Ga-PSMA PET/CT.

Xanthogranulomatous inflammatory disease is a rare and benign condition that affects various organs. Due to their aggressive nature, the clinical and radiological findings of xanthogranulomatous inflammatory diseases are often misdiagnosed as malignant neoplasms. Prostate cancer metastases are most prevalent in lymph nodes and bones, with less common locations including the lung, liver, and brain.

A New Means to Generate Liposomes by Rehydrating Engineered Lipid Nanoconstructs.

The concept and feasibility of producing liposomes by rehydrating engineered lipid nanoconstructs are demonstrated in this study. Nanoconstructs of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) were produced using a microfluidic delivery probe integrated with an atomic force microscope. The subsequent rehydration of these POPC constructs led to the formation of liposomes, most of which remained adhered to the surface.

Microbial Art Fixation on Agar Plate: MicArt Fixation for Microbiology Teaching.

Art based science materials engage students for learning all of the unseen microscobic creatures in easy way microbiology field. In this study we aimed to visualize bacterial and fungal species in artistic way. Inoculation of the colourful strains on agar plate as painting the agar with bacteria, provides beautiful round scenes and clear reminiscence related with the species learning for microbe world.