Publications by authors named "Muddassir Aliniazee"
Article Synopsis
- Female smokers experience a more rapid decline in lung function compared to male smokers, raising questions about the role of estrogen in lung disease related to cigarette smoke.
- Research utilizing mouse models indicates that female mice are more vulnerable to cigarette smoke-induced lung damage, with younger female mice developing emphysema sooner than males.
- A study involving ovariectomized female mice highlighted that lack of estrogen increases susceptibility to lung disease from cigarette smoke, as evidenced by significant changes in lung tissue and biological markers that were mitigated by estrogen treatment.
Endocrinology
February 2014
Article Synopsis
- The study investigates how estrogen deficiency affects the aging lungs of female mice, finding that old estrogen-deficient mice had reduced lung volume and surface area.
- Estrogen replacement therapy improved lung characteristics in these mice, restoring them to levels similar to younger mice.
- The research highlights the potential role of estrogens in preventing age-related lung changes, suggesting implications for treating aging-related lung diseases in women.
