Publications by authors named "Mudan Guo"
Titanium (Ti) implants are widely used in orthopedic and dental applications due to their excellent biocompatibility and mechanical properties. However, bacterial adhesion and subsequent biofilm formation on implant surfaces pose a significant risk of postoperative infections and complications. Conventional surface modifications often lack long-lasting antibacterial efficacy, necessitating the development of novel coatings with enhanced antimicrobial properties.
View Article and Find Full Text PDFBackground: The clinical applications of dispensing granules (DG) have increased dramatically. However, it is controversial whether the DG has the same quality and efficacy compared with traditional decoction (TD). In this study, the contents of main compounds, hypoglycemic effects, and potential mechanism of Coptidis Rhizoma (CR) and Scutellaria-coptis (SC), constituted of a 1:1 mixture of CR and Scutellariae Radix (SR), in the forms of TD and DG were compared.
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- Researchers created a new compound called ligustrazine diselenide (Se2) to help treat lung cancer.
- Tests showed that Se2 can stop the growth of cancer cells and make them die, especially in human lung adenocarcinoma cells.
- Se2 works by blocking certain pathways in the cells, leading to less movement and growth of the cancer cells, making it a promising option for lung cancer treatment.