P2X7 receptor antagonist recovers ileum myenteric neurons after experimental ulcerative colitis.

Background: The P2X7 receptor is expressed by enteric neurons and enteric glial cells. Studies have demonstrated that administration of a P2X7 receptor antagonist, brilliant blue G (BBG), prevents neuronal loss.

Aim: To report the effects of BBG in ileum enteric neurons immunoreactive (ir) following experimental ulcerative colitis in .