Ginkgolic acids induce HepG2 cell death via a combination of apoptosis, autophagy and the mitochondrial pathway.

Ginkgolic acids may induce malignant cell death via the B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax)/Bcl-2 apoptosis pathway. Concurrently, apoptosis, autophagy and mitochondrial dysfunction may also be involved in bringing about this endpoint. The anticancer effect of Ginkgolic acids (GAs) was investigated using the HepG2 cell line.

Autophagy is involved in recombinant Newcastle disease virus (rL-RVG)-induced cell death of stomach adenocarcinoma cells in vitro.

Oncolytic viruses can kill malignant cells while sparing normal cells. Multiple pathways are involved in this action. The antitumor effects of viral infection on SGC-7901 and AGS cells were investigated.

Properties of extracellular matrix-like scaffolds for the growth and differentiation of endothelial progenitor cells.

Background: To provide a new strategy for constructing small vascular graft, the survival conditions of endothelial progenitor cells (EPCs), which were seeded on two different groups of extracellular matrix (ECM) scaffolds were studied in vitro.

Materials And Methods: The scaffold was made with a mixture of fibrinogen, fibronectin, and laminin, which solidified to form unpressed structure. A 1N force could make it to be pressed.