Publications by authors named "Mubeena Aziz"
Background: Women with polycystic ovary syndrome (PCOS) often change their metabolic profile over time to decrease levels of androgens while often gaining a propensity for the development of the metabolic syndrome. Recent discoveries indicate that microRNAs (miRNAs) play a role in the development of PCOS and constitute potential biomarkers for PCOS. We aimed to identify miRNAs associated with the development of an impaired metabolic profile in women with PCOS, in a follow-up study, compared with women without PCOS.
View Article and Find Full Text PDFBone mass density in lean and overweight women with polycystic ovary syndrome.
Scand J Clin Lab Invest
May 2022
Article Synopsis
- The study investigates how polycystic ovary syndrome (PCOS) affects bone mineral density in premenopausal women, finding that women with PCOS have lower bone density in the lumbar spine compared to healthy controls.
- Total lean body mass was identified as the key factor influencing bone mineral density, highlighting its importance for individuals with PCOS.
- The findings suggest that while women with PCOS face challenges to their bone health, factors like androgen levels and insulin resistance do not significantly impact lumbar bone density.
Thromboembolic events constitute a serious complication to assisted reproductive technology, and this is a case report of thrombosis after in vitro fertilisation. A 30-year-old woman had a positive pregnancy test, but she experienced shortness of breath 12 days after oocyte retrieval. D-dimer concentration was elevated, and lung scintigraphy demonstrated an infarction.
View Article and Find Full Text PDFBackground: Polycystic ovary syndrome (PCOS) defined by the Rotterdam criteria does not take into account the unhealthy metabolic profile of the syndrome with increased insulin resistance (IR) and overweight favoring development of type 2 diabetes, hypertension and cardiovascular disease (CVD). We assess three vasoactive peptides associated with CVD in women with PCOS.
Method: Plasma levels of mid-regional pro-atrial natriuretic peptide (MR-proANP), copeptin and mid-regional pro-adrenomedullin (MR-proADM) were measured in 98 PCOS patients and 46 age- and BMI-matched healthy women.
Objectives: The objective of this study is to investigate plasma endogenous thrombin generation in four different phenotypes of polycystic ovary syndrome (PCOS) defined by Body Mass Index (BMI) and insulin resistance (IR). PCOS is diagnosed according to the Rotterdam criteria.
Design: Multicenter cross-sectional study.
Polycystic ovary syndrome: cardiovascular risk factors according to specific phenotypes.
Acta Obstet Gynecol Scand
October 2015
Introduction: Polycystic ovary syndrome (PCOS) is associated with obesity and insulin resistance. The objective of this cross-sectional study was to investigate the impact of insulin resistance and body mass index (BMI) on inflammatory and hemostatic variables associated with long-term risk of cardiovascular disease in women with PCOS.
Material And Methods: 149 premenopausal women with PCOS were recruited consecutively from April 2010 to February 2012 at three Danish University Hospitals.