Publications by authors named "Mubeen Ali"
Background And Objectives: Measuring postoperative outcomes after complex cancer operations such as pancreatectomy is vital to improve cancer surgery in low- and middle-income countries (LMICs); however, such data is often limited. This study aimed to review existing research and obtain baseline estimates for postoperative mortality and morbidity after pancreatic cancer surgery in LMICs.
Methods: PubMed, Embase, Web of Science Core Collection, and Global Index Medicus were systematically searched for original articles published between January 2005 and May 2022.
Frequency and Outcome of Postoperative Atrial Fibrillation Following Mitral Valve Replacement for Mitral Stenosis.
J Coll Physicians Surg Pak
October 2024
Article Synopsis
- The study aimed to evaluate how often postoperative atrial fibrillation (POAF) occurs and its effects on in-hospital and 30-day mortality and morbidity in patients undergoing mitral valve replacement (MVR).
- Conducted at a cardiac surgery department in Pakistan, it included 186 patients aged 20-70 with severe mitral stenosis who underwent surgery, tracking the incidence of POAF and associated outcomes.
- Results showed that 19.4% of patients developed POAF, leading to longer ICU and hospital stays, higher mortality rates, and complications such as embolic strokes and congestive heart failure within 30 days.
A retrospective review of the outcomes of patients who underwent endoscopic myringoplasties in our institution was conducted. The aim was to highlight our results with this procedure. The database of patient records was manually checked, and the patients who had undergone Endoscopic Myringoplasties were identified, and their demographics, admitting notes, operating notes, and discharge summaries were reviewed.
View Article and Find Full Text PDFBackground: The plasma cell malignancy, multiple myeloma (MM), remains incurable despite advanced treatment protocols. Overexpression of Bcl-2 (an anti-apoptotic protein), in MM harboring the translocation (11;14), contributes to resistance to prior therapy. Venetoclax, a selective oral inhibitor of BCL-2 is a novel agent that shows promise as a therapeutic agent.
View Article and Find Full Text PDFSuppression of Cytokine Signalling-3 (SOCS-3) modulates the inflammatory pathways responsible for vascular stability. Therefore, we aimed to estimate SOCS-3 levels in 2nd trimester pregnant females and correlate it with blood pressure. A case control study recruiting (n=111) females was conducted at the Aga Khan University.
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